Yıl 2017, Cilt 15, Sayı 2, Sayfalar 124 - 129 2017-08-11

Grafen Oksit-Polianilin Nanokompozit Temelli Amperometrik Glukoz Biyosensörü Geliştirilmesi
Development of Graphene Oxide-Polyaniline Nanocomposite Based Amperometric Glucose Biosensor

Sadık Çoğal [1]

177 467

Bu çalışmada, Pt elektrot, grafen oksit-polianilin (GO-PANI) nanokompoziti ile modifiye edilerek amperometrik glukoz biyosensörü geliştirilmesinde kullanılmıştır. Modifiye edilmiş Pt elektroda glukoz oksidaz (GOD) enzimi çapraz bağlayıcı kullanılarak immobilize edilmiştir. Bu şekilde hazırlanan Pt/GO-PANI/GOD biyosensörünün optimum çalışma koşullarında amperometrik yöntemle glukoza karşı cevabı çalışılmış ve 36.11 μA mM-1 cm-2 hassasiyet, 0.59-9.15 mM lineer çalışma aralığı ve 0.24 mM tayin limiti sergilemiştir. Geliştirilen glukoz biyosensörü üzerine askorbik asit (AA) ve ürik asidin (UA) girişim etkileri incelenmiş ve biyosensörün glukoza karşı oldukça seçici olduğu gözlenmiştir.

In this study, Pt electrode was modified with graphene oxide-polyaniline (GO-PANI) nanocomposite and used in the fabrication of amperometric glucose biosensor. Glucose oxidase (GOD) was immobilized on the modified Pt electrode by using a cross-linking agent. The proposed Pt/GO-PANI/GOD biosensor exhibited a sensitivity value of 36.11 μA mM-1 cm-2 with a linear range of 0.59-9.15 mM and the detection limit of 0.24 mM under optimum conditions. The interference effects of ascorbic acid (AA) and uric acid (UA) on the developed glucose biosensor were studied, and it was observed that the biosensor was highly selective to glucose.

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Dergi Bölümü Araştırma Makaleleri
Yazarlar

Orcid: http://orcid.org/0000-0001-8904-1332
Yazar: Sadık Çoğal

Bibtex @araştırma makalesi { akademik-gida333663, journal = {Akademik Gıda}, issn = {1304-7582}, eissn = {2148-015X}, address = {Sidas Medya Ajans Tanıtım Danışmanlık Ltd. Şti.}, year = {2017}, volume = {15}, pages = {124 - 129}, doi = {10.24323/akademik-gida.333663}, title = {Grafen Oksit-Polianilin Nanokompozit Temelli Amperometrik Glukoz Biyosensörü Geliştirilmesi}, key = {cite}, author = {Çoğal, Sadık} }
APA Çoğal, S . (2017). Grafen Oksit-Polianilin Nanokompozit Temelli Amperometrik Glukoz Biyosensörü Geliştirilmesi. Akademik Gıda, 15 (2), 124-129. DOI: 10.24323/akademik-gida.333663
MLA Çoğal, S . "Grafen Oksit-Polianilin Nanokompozit Temelli Amperometrik Glukoz Biyosensörü Geliştirilmesi". Akademik Gıda 15 (2017): 124-129 <http://dergipark.gov.tr/akademik-gida/issue/30836/333663>
Chicago Çoğal, S . "Grafen Oksit-Polianilin Nanokompozit Temelli Amperometrik Glukoz Biyosensörü Geliştirilmesi". Akademik Gıda 15 (2017): 124-129
RIS TY - JOUR T1 - Grafen Oksit-Polianilin Nanokompozit Temelli Amperometrik Glukoz Biyosensörü Geliştirilmesi AU - Sadık Çoğal Y1 - 2017 PY - 2017 N1 - doi: 10.24323/akademik-gida.333663 DO - 10.24323/akademik-gida.333663 T2 - Akademik Gıda JF - Journal JO - JOR SP - 124 EP - 129 VL - 15 IS - 2 SN - 1304-7582-2148-015X M3 - doi: 10.24323/akademik-gida.333663 UR - http://dx.doi.org/10.24323/akademik-gida.333663 Y2 - 2017 ER -
EndNote %0 Akademik Gıda Grafen Oksit-Polianilin Nanokompozit Temelli Amperometrik Glukoz Biyosensörü Geliştirilmesi %A Sadık Çoğal %T Grafen Oksit-Polianilin Nanokompozit Temelli Amperometrik Glukoz Biyosensörü Geliştirilmesi %D 2017 %J Akademik Gıda %P 1304-7582-2148-015X %V 15 %N 2 %R doi: 10.24323/akademik-gida.333663 %U 10.24323/akademik-gida.333663
ISNAD Çoğal, Sadık . "Grafen Oksit-Polianilin Nanokompozit Temelli Amperometrik Glukoz Biyosensörü Geliştirilmesi". Akademik Gıda 15 / 2 (Ağustos 2017): 124-129. http://dx.doi.org/10.24323/akademik-gida.333663