Cilt 3, Sayı 1, Sayfalar 31 - 42

Phytochemical screening, antiproliferative and cytotoxic activities of the mosses Rhytidiadelphus triquetrus (Hedw.) Warnst. and Tortella tortuosa (Hedw.) Limpr.

Muhammet Şamil YAĞLIOĞLU [1] , Gökhan ABAY [2] , İbrahim DEMİRTAŞ [3] , Ayşe ŞAHİN YAĞLIOĞLU [4]

63 85

The paper presents information about the phytochemical analysis, antiproliferative and cytotoxic activities of Rhytidiadelphus triquetrus and Tortella tortuosa extracts. The cytotoxic activities of some extracts shows highest antiproliferative activities were detected with Lactate Dehydrogenase Leakage Assay. Sixteen components obtained from hexane extracts were determined by GC/MS. Palmitic acid was identified as the main component. The phenolic components of the other extracts were determined by HPLC-TOF/MS. 4-hydroxy benzoic acid, salicylic acid, gallic acid, caffeic acid, and gensitic acid were detected as the main components in all extracts. The hexane, chloroform, ethyl acetate extracts of studied mosses and the EtOAc and hexane extracts of R. triquetrus showed statistically significant antiproliferative activities.


Anticancer; cytotoxic; C6 cancer cell; HeLa cancer cell; mosses
  • Asakawa, Y., 2007. Biologically active compounds from bryophytes. Pure Appl. Chem. 79, 557-580.
  • Asakawa, Y., Ludwiczuk, A., Nagashima, F., 2013. Phytochemical and biological studies of bryophytes. Phytochemistry 91, 52-80.
  • Baynes, J.W., Dominiczak, M.H., 2005. Medical Biochemistry 2ed. Elsevier Mosby.
  • Brinkmeier, E., Hahn, H., Seeger, T., Geiger, H., Zinsmeister, H.D., 1999. Seasonal variation in flavonoid concentrations of mosses. Biochem. Syst. Ecol. 27, 427-435.
  • Burr, G.O., Burr, M.M., Miller, E., 1930. On the nature and role of the fatty acids essential in nutrition. J. Biol. Chem. 86, 587-621.
  • Bwai, M.D., Adedirin, O., Akanji, F.T., Muhammad, K.J., Idoko, O., Useh, M.U., 2013. Physicochemical properties, fatty acids profiles and antioxidant properties of seed oil of breadfruit (Treculia africana). Int. J. Res. Pharm. Sci. 3, 44-54.
  • Clifford, M.N., 2000. Chlorogenic acids and other cinnamates - nature, occurrence, dietary burden, absorption and metabolism. J. Sci. Food Agr. 80, 1033-1043.
  • Demirtas, I., Sahin, A., 2013. Bioactive volatile content of the stem and root of Centaurea carduiformis DC. subsp. carduiformis var. carduiformis. J. Chem. Ny 2013, 1-6.
  • Demirtas, I., Sahin, A., Ayhan, B., Tekin, S., Telci, I., 2009. Antiproliferative effects of the methanolic extracts of Sideritis libanotica Labill. subsp linearis. Rec. Nat. Prod. 3, 104-109.
  • Elibol, B., Ezer, T., Kara, R., Çelik, G.Y., Çolak, E., 2013. Antifungal and antibacterial effects of some acrocarpic mosses. Afr. J. Biotechnol. 10, 986-989.
  • Faried, A., Kurnia, D., Faried, L.S., Usman, N., Miyazaki, T., Kato, H., Kuwano, H., 2007. Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines. Int. J. Oncol. 30, 605-613.
  • Karakus, G., Akin Polat, Z., Sahin Yaglioglu, A., Karahan, M., Yenidunya, A.F., 2013. Synthesis, characterization, and assessment of cytotoxic, antiproliferative, and antiangiogenic effects of a novel procainamide hydrochloride-poly(maleic anhydride-co-styrene) conjugate. J. Biomater. Sci. Polym. Ed. 24, 1260-1276.
  • Kļaviņa, L., Bikovens, O., Steinberga, I., Maksimova, V., Eglite, L., 2012. Characterization of chemical composition of some bryophytes common in Latvia. Environ. and Exp. Biol. 10, 27-34.
  • Narisawa, T., Takahashi, M., Kotanagi, H., Kusaka, H., Yamazaki, Y., Koyama, H., Fukaura, Y., Nishizawa, Y., Kotsugai, M., Isoda, Y., et al., 1991. Inhibitory effect of dietary perilla oil rich in the n-3 polyunsaturated fatty acid alpha-linolenic acid on colon carcinogenesis in rats. Jpn. J. Cancer Res. 82, 1089-1096.
  • Patil, P.D., Chavan, N.S., 2012. Potential testing of fatty acids from mangrove Aegiceras corniculatum (L.) Blanco. Int. J. Pharm. Pharm. Sci. 4, 569-571.
  • Sabovljević, M., Bijelović, A., Grubišić, D., 2001. Bryophytes as a potential source of medicinal compounds. Lek. Sirov. 21, 17-29.
  • Sahin Yaglıoglu, A., Akdulum, B., Erenler, R., Demirtas, I., Telci, I., Tekin, S., 2013. Antiproliferative activity of pentadeca-(8E, 13Z) dien-11-yn-2-one and (E)-1, 8-pentadecadiene from Echinacea pallida (Nutt.) Nutt. roots. Med. Chem. Res. 22, 2946-2953.
  • Savaroglu, F., Ilhan, S., Filik-Iscen, C., 2011. An evaluation of the antimicrobial activity of some Turkish mosses. J. Med. Plants. Res. 5, 3286-3292.
  • Schofield, W.B., 2001. Introduction to Bryology. The Blackburn Press, New Jersey.
  • Smith, A.J.E., 2004. The Moss Flora of Britain and Ireland, 2 ed. Cambridge University Press, Cambridge.
  • Smith, G.I., Atherton, P., Reeds, D.N., Mohammed, B.S., Rankin, D., Rennie, M.J., Mittendorfer, B., 2011. Omega-3 polyunsaturated fatty acids augment the muscle protein anabolic response to hyperinsulinaemia-hyperaminoacidaemia in healthy young and middle-aged men and women. Clin. Sci. 121, 267-278.
  • Üçüncü, O., Cansu, T.B., Özdemir, T., Karaoğlu, Ş.A., Yayli, N., 2010. Chemical composition and antimicrobial activity of the essential oils of mosses (Tortula muralis Hedw., Homalothecium lutescens (Hedw.) H. Rob., Hypnum cupressiforme Hedw., and Pohlia nutans (Hedw.) Lindb.) from Turkey. Turk. J. Chem. 34, 825-834.
  • Vanderpoorten, A., Goffinet, B., 2009. Introduction to Bryophytes. Cambridge University Press New York.
  • Vargas, M.H., 2000. IC50 ve IC75 values ED50 plus v1.0 programs. Instituto Nacional de Enfermedades Respiratorias.
  • Whitney, E., Rolfes, S.R., 2008. Understanding Nutrition, 11 ed. Thomson Wadsworth, California, p. 154.
Konular Yaşam Bilimleri
Dergi Bölümü Araştırma Makaleleri
Yazarlar

Yazar: Muhammet Şamil YAĞLIOĞLU
E-posta: gokhanabay@gmail.com
Ülke: Turkey


Yazar: Gökhan ABAY
E-posta: gokhanabay@gmail.com
Ülke: Turkey


Yazar: İbrahim DEMİRTAŞ
E-posta: ibdemirtas@gmail.com

Yazar: Ayşe ŞAHİN YAĞLIOĞLU
E-posta: aysesahin1@gmail.com

Bibtex @araştırma makalesi { anatolianbryology317785, journal = {Anatolian Bryology}, issn = {2149-5920}, address = {Çankırı Karatekin Üniversitesi}, year = {}, volume = {3}, pages = {31 - 42}, doi = {}, title = {Phytochemical screening, antiproliferative and cytotoxic activities of the mosses Rhytidiadelphus triquetrus (Hedw.) Warnst. and Tortella tortuosa (Hedw.) Limpr.}, language = {en}, key = {cite}, author = {DEMİRTAŞ, İbrahim and YAĞLIOĞLU, Muhammet Şamil and ABAY, Gökhan and ŞAHİN YAĞLIOĞLU, Ayşe} }
APA YAĞLIOĞLU, M , ABAY, G , DEMİRTAŞ, İ , ŞAHİN YAĞLIOĞLU, A . (). Phytochemical screening, antiproliferative and cytotoxic activities of the mosses Rhytidiadelphus triquetrus (Hedw.) Warnst. and Tortella tortuosa (Hedw.) Limpr.. Anatolian Bryology, 3 (1), 31-42. Retrieved from http://dergipark.gov.tr/anatolianbryology/issue/30539/317785
MLA YAĞLIOĞLU, M , ABAY, G , DEMİRTAŞ, İ , ŞAHİN YAĞLIOĞLU, A . "Phytochemical screening, antiproliferative and cytotoxic activities of the mosses Rhytidiadelphus triquetrus (Hedw.) Warnst. and Tortella tortuosa (Hedw.) Limpr.". Anatolian Bryology 3 (): 31-42 <http://dergipark.gov.tr/anatolianbryology/issue/30539/317785>
Chicago YAĞLIOĞLU, M , ABAY, G , DEMİRTAŞ, İ , ŞAHİN YAĞLIOĞLU, A . "Phytochemical screening, antiproliferative and cytotoxic activities of the mosses Rhytidiadelphus triquetrus (Hedw.) Warnst. and Tortella tortuosa (Hedw.) Limpr.". Anatolian Bryology 3 (): 31-42
RIS TY - JOUR T1 - Phytochemical screening, antiproliferative and cytotoxic activities of the mosses Rhytidiadelphus triquetrus (Hedw.) Warnst. and Tortella tortuosa (Hedw.) Limpr. AU - Muhammet Şamil YAĞLIOĞLU , Gökhan ABAY , İbrahim DEMİRTAŞ , Ayşe ŞAHİN YAĞLIOĞLU Y1 - 2017 PY - 2017 N1 - DO - T2 - Anatolian Bryology JF - Journal JO - JOR SP - 31 EP - 42 VL - 3 IS - 1 SN - 2149-5920-2458-8474 M3 - UR - Y2 - 2017 ER -
EndNote %0 Anatolian Bryology Phytochemical screening, antiproliferative and cytotoxic activities of the mosses Rhytidiadelphus triquetrus (Hedw.) Warnst. and Tortella tortuosa (Hedw.) Limpr. %A Muhammet Şamil YAĞLIOĞLU , Gökhan ABAY , İbrahim DEMİRTAŞ , Ayşe ŞAHİN YAĞLIOĞLU %T Phytochemical screening, antiproliferative and cytotoxic activities of the mosses Rhytidiadelphus triquetrus (Hedw.) Warnst. and Tortella tortuosa (Hedw.) Limpr. %D 2017 %J Anatolian Bryology %P 2149-5920-2458-8474 %V 3 %N 1 %R %U