DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI

İbrahim ÜÇGÜL [1] , Sultan ARAS [2]

68 177

Deselülerize edilmiş doku ve organlar çeşitli doku mühendisliği ve rejeneratif tıp uygulamalarında başarıyla kullanılmaktadır. Ekstraselüler matristen elde edilen biyolojik bir iskele, işlem görecek dokudan hücreleri etkin bir şekilde ortadan kaldıran çeşitli deselülerizasyon yöntemleri ile üretilebilir. Kullanılan deselülerizasyon yöntemleri dokuların ve organların yapısına göre değişir. Hücrelerin bir dokudan çıkarılması, dokunun kaynağına ve kullanılan spesifik fiziksel, kimyasal ve enzimatik yöntemlere bağlıdır. Bu yöntemlerin her biri geri kalan hücre dışı matrisin (ECM) yapısındaki biyokimyasal bileşimini, dokunun ince yapısını  (ultrastrüktürünü) ve mekanik davranışını etkiler. Bu makalede en sık kullanılan deselülerizasyon yöntemleri tanıtılarak ve bu yöntemlerin biyolojik doku iskelesi materyali üzerindeki etkileri ele alınmaktadır.

Deselülerizasyon, Ekstraselüler Matris, Doku mühendisliği (TE)
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Konular Mühendislik ve Temel Bilimler
Dergi Bölümü TEKNİK BİLİMLER
Yazarlar

Yazar: İbrahim ÜÇGÜL
Kurum: Süleyman Demirel Üniversitesi
Ülke: Turkey


Yazar: Sultan ARAS
Ülke: Turkey


Bibtex @derleme { anka354053, journal = {Anka E-Dergi}, issn = {2148-7138}, address = {Süleyman Demirel Üniversitesi}, year = {}, volume = {2}, pages = {19 - 34}, doi = {}, title = {DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI}, key = {cite}, author = {ÜÇGÜL, İbrahim and ARAS, Sultan} }
APA ÜÇGÜL, İ , ARAS, S . (). DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI. Anka E-Dergi, 2 (2), 19-34. Retrieved from http://dergipark.gov.tr/anka/issue/33406/354053
MLA ÜÇGÜL, İ , ARAS, S . "DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI". Anka E-Dergi 2 (): 19-34 <http://dergipark.gov.tr/anka/issue/33406/354053>
Chicago ÜÇGÜL, İ , ARAS, S . "DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI". Anka E-Dergi 2 (): 19-34
RIS TY - JOUR T1 - DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI AU - İbrahim ÜÇGÜL , Sultan ARAS Y1 - 2018 PY - 2018 N1 - DO - T2 - Anka E-Dergi JF - Journal JO - JOR SP - 19 EP - 34 VL - 2 IS - 2 SN - 2148-7138- M3 - UR - Y2 - 2017 ER -
EndNote %0 Anka E-Dergi DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI %A İbrahim ÜÇGÜL , Sultan ARAS %T DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI %D 2018 %J Anka E-Dergi %P 2148-7138- %V 2 %N 2 %R %U
ISNAD ÜÇGÜL, İbrahim , ARAS, Sultan . "DESELÜLERİZASYON YÖNTEMLERİ VE DOKULARDA KULLANIMI". Anka E-Dergi 2 / 2 19-34.