Year 2017, Volume 13, Issue 1, Pages 105 - 112 2017-03-30

Plasma Modification of 3D Hydrogels for Cell Culture Applications

Emel Sokullu [1]

231 217

The aim of this study was to examine plasma effect on to the different structures including 2D glass slides and 3D treated Gelma hydrogels with an increased range of biodegradation rates for more rapid in vivo biodegradation in tissue engineering and bioactive factor delivery applications. Considering the known excellent biocompatibility of GELMA, we envision that this hydrogel material could be potentially used in tissue engineering and for the purpose of directing the growth and migration of cells. Another dimension of this study is plasma patterning of the substrates. This method has been employed to form diverse networks of different cell types for investigations involving migration, signaling, tissue formation, and the behavior and interactions of neurons arraigned in a network. As a result of these, we investigated whether the swelling behavior, degradation profiles, and cell proliferation properties of photocrosslinked hydrogels formed by methacrylated and plasma treated are tunable by varying the degree of plasma conditions. The potential applicability of these photocrosslinked GELMA hydrogels as a carrier of embryonic stem cells (ESCs) was also examined in vitro.


Plasma treatment, hydrogels, 3D Cell Culture, embryonic stem cells (ESCs)
  • [1] Y. Hong, H.Q. Song, Y.H. Gong, Z.W. Mao, C.Y. Gao, J.C. Shen, “Covalently crosslinked chitosan hydrogel: properties of in vitro degradation and chondrocyte encapsulation” Acta Biomater., (2007), 3:23.
Subjects Engineering
Journal Section Articles
Authors

Author: Emel Sokullu

Bibtex @research article { cbayarfbe302649, journal = {Celal Bayar University Journal of Science}, issn = {1305-130X}, eissn = {1305-1385}, address = {Celal Bayar University}, year = {2017}, volume = {13}, pages = {105 - 112}, doi = {10.18466/cbayarfbe.302649}, title = {Plasma Modification of 3D Hydrogels for Cell Culture Applications}, key = {cite}, author = {Sokullu, Emel} }
APA Sokullu, E . (2017). Plasma Modification of 3D Hydrogels for Cell Culture Applications. Celal Bayar University Journal of Science, 13 (1), 105-112. DOI: 10.18466/cbayarfbe.302649
MLA Sokullu, E . "Plasma Modification of 3D Hydrogels for Cell Culture Applications". Celal Bayar University Journal of Science 13 (2017): 105-112 <http://dergipark.gov.tr/cbayarfbe/issue/28447/302649>
Chicago Sokullu, E . "Plasma Modification of 3D Hydrogels for Cell Culture Applications". Celal Bayar University Journal of Science 13 (2017): 105-112
RIS TY - JOUR T1 - Plasma Modification of 3D Hydrogels for Cell Culture Applications AU - Emel Sokullu Y1 - 2017 PY - 2017 N1 - doi: 10.18466/cbayarfbe.302649 DO - 10.18466/cbayarfbe.302649 T2 - Celal Bayar University Journal of Science JF - Journal JO - JOR SP - 105 EP - 112 VL - 13 IS - 1 SN - 1305-130X-1305-1385 M3 - doi: 10.18466/cbayarfbe.302649 UR - https://doi.org/10.18466/cbayarfbe.302649 Y2 - 2019 ER -
EndNote %0 Celal Bayar University Journal of Science Plasma Modification of 3D Hydrogels for Cell Culture Applications %A Emel Sokullu %T Plasma Modification of 3D Hydrogels for Cell Culture Applications %D 2017 %J Celal Bayar University Journal of Science %P 1305-130X-1305-1385 %V 13 %N 1 %R doi: 10.18466/cbayarfbe.302649 %U 10.18466/cbayarfbe.302649
ISNAD Sokullu, Emel . "Plasma Modification of 3D Hydrogels for Cell Culture Applications". Celal Bayar University Journal of Science 13 / 1 (March 2017): 105-112. https://doi.org/10.18466/cbayarfbe.302649