Yıl 2018, Cilt 6, Sayı 1, Sayfalar 231 - 239 2018-01-31

Parkinson Disease and Associated Genes
Parkinson Hastalığı ve İlişkili Olduğu Genler

Yener Kurman [1]

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Parkinson disease is the second most common neurodegenerative disease after Alzheimer's disease. Essential pathological findings of Parkinson's disease; progressive loss of dopaminergic neurons in the substantia nigra pars compacta and striatum in the midbrain and accumulation of inclusions in the neurons called Lewy bodies. Many researchers have shown that Parkinson's disease is rarely caused by familial, especially sporadic factors (environmental and genetics) contribute to the initiation and progression of this disease. 26 gene loci related to Parkinson's disease have been identified until now. Aims of this study, contributing to the literature on genes associated with Parkinson's disease.

Parkinson Hastalığı, Alzheimer hastalığından sonra ikinci en sık görülen nörodejeneratif bir hastalıktır. Parkinson hastalığının temel patolojik bulguları; orta beyindeki substantia nigra pars compacta ve striatumdaki dopaminerjik nöronların ilerleyici kaybı ve Lewy cisimcikleri olarak adlandırılan inklüzyonların nöronlarda birikimidir. Birçok araştırmacı, Parkinson hastalığının nadiren ailesel olduğunu, özellikle sporadik faktörlerin (çevresel ve genetik) bu hastalığın başlamasına ve ilerlemesine neden olduğunu göstermiştir. Bugüne kadar Parkinson hastalığına bağlı 26 gen lokusu tanımlanmıştır. Bu çalışmanın amacı, Parkinson hastalığı ile ilişkili genler üzerine literatüre katkı sağlamaktır.

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Birincil Dil tr
Konular Mühendislik ve Temel Bilimler
Dergi Bölümü Makaleler
Yazarlar

Yazar: Yener Kurman (Sorumlu Yazar)
Ülke: Turkey


Bibtex @derleme { dubited359368, journal = {Düzce Üniversitesi Bilim ve Teknoloji Dergisi}, issn = {}, eissn = {2148-2446}, address = {Düzce Üniversitesi}, year = {2018}, volume = {6}, pages = {231 - 239}, doi = {10.29130/dubited.359368}, title = {Parkinson Hastalığı ve İlişkili Olduğu Genler}, key = {cite}, author = {Kurman, Yener} }
APA Kurman, Y . (2018). Parkinson Hastalığı ve İlişkili Olduğu Genler. Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 6 (1), 231-239. DOI: 10.29130/dubited.359368
MLA Kurman, Y . "Parkinson Hastalığı ve İlişkili Olduğu Genler". Düzce Üniversitesi Bilim ve Teknoloji Dergisi 6 (2018): 231-239 <http://dergipark.gov.tr/dubited/issue/34777/359368>
Chicago Kurman, Y . "Parkinson Hastalığı ve İlişkili Olduğu Genler". Düzce Üniversitesi Bilim ve Teknoloji Dergisi 6 (2018): 231-239
RIS TY - JOUR T1 - Parkinson Hastalığı ve İlişkili Olduğu Genler AU - Yener Kurman Y1 - 2018 PY - 2018 N1 - doi: 10.29130/dubited.359368 DO - 10.29130/dubited.359368 T2 - Düzce Üniversitesi Bilim ve Teknoloji Dergisi JF - Journal JO - JOR SP - 231 EP - 239 VL - 6 IS - 1 SN - -2148-2446 M3 - doi: 10.29130/dubited.359368 UR - http://dx.doi.org/10.29130/dubited.359368 Y2 - 2017 ER -
EndNote %0 Düzce Üniversitesi Bilim ve Teknoloji Dergisi Parkinson Hastalığı ve İlişkili Olduğu Genler %A Yener Kurman %T Parkinson Hastalığı ve İlişkili Olduğu Genler %D 2018 %J Düzce Üniversitesi Bilim ve Teknoloji Dergisi %P -2148-2446 %V 6 %N 1 %R doi: 10.29130/dubited.359368 %U 10.29130/dubited.359368
ISNAD Kurman, Yener . "Parkinson Hastalığı ve İlişkili Olduğu Genler". Düzce Üniversitesi Bilim ve Teknoloji Dergisi 6 / 1 (Ocak 2018): 231-239. http://dx.doi.org/10.29130/dubited.359368