Cilt 3, Sayı 1, Sayfalar 16 - 24 2017-03-04

Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography

Hasan Ari [1] , Selvi Oztas Cosar [2] , Selma Ari [3] , Kubra Doganay [4] , Cihan Aydin [5] , Nadir Emlek [6] , Nuran Celiloglu [7] , Ahmet Seckin Cetinkaya [8] , Tahsin Bozat [9] , Mehmet Melek [10]

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Objectives. Contrast-induced nephropathy (CIN) is the third most common cause of acute renal failure that occurred in the hospital. In Turkey, there is not enough data about the frequency of CIN in cardiological interventions. Increased contrast volume and creatinin value are related with CIN. We also investigated the CIN predictors. Methods. A total of 2604 patients who underwent coronary angiography or percutaneous coronary intervention (PCI) in our hospital were prospectively evaluated in terms of CIN. The definition of CIN includes absolute (≥0.5mg/dl) or relative increase (≥25%) in serum creatinine at 48-72 h after exposure to a contrast agent compared to baseline serum creatinine values. Results. CIN was detected in 13.6% (355 patients) of 2604 patients. According to the procedure; CIN rate was 13.3% (280 of 2108 patients) in coronary angiography, 13.08% (50 of 382 patients) in elective PCI and 21.49% (25 of 114 patients) in primary PCI. Compared with each of these three groups patients, CIN rate was significantly higher in primary PCI group than coronary angiography (p=0.009) and elective PCI (p=0.02) groups. In multivariate analysis, age (odds ratio [OR]=1.04; 95% confidence interval [CI], 1.02-1.06; p<0.001), glomerular filtration rate (OR=0.99; 95% CI, 0.98-0.99; p<0.001), contrast volume (OR=1.14; 95% CI, 1.007-1.21; p<0.006), contrast volume to creatinine ratio (OR=1.01; 95% CI, 1.009-1.02; p<0.001), three vessel disease (OR=1.77, 95% CI, 1.24-2.51; p=0.001) were independent predictors of CIN. Conclusions. In our patient population, the incidence of CIN was found to be 13.6% in cardiological interventions. In emergency interventions, incidence of CIN was increased. We found that contrast volume to creatinine ratio is predictor of CIN. 

Contrast-induced nephropathy,coronary angiography,percutaneous coronary intervention,renal failure,contrast media
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Konular Sağlık Bilimleri
Dergi Bölümü Original Article
Yazarlar

Yazar: Hasan Ari
E-posta: hasanari03@yahoo.com
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Yazar: Selvi Oztas Cosar
E-posta: selvi35byih@hotmail.com
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Yazar: Selma Ari
E-posta: selmakulekci@yahoo.com.tr
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Yazar: Kubra Doganay
E-posta: kubradoganay32@yahoo.com
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Yazar: Cihan Aydin
E-posta: drcihanaydin@hotmail.com
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Yazar: Nadir Emlek
E-posta: medianus@hotmail.com
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Yazar: Nuran Celiloglu
E-posta: drnuran@gmail.com
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Yazar: Ahmet Seckin Cetinkaya
E-posta: seckincet@gmail.com
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Yazar: Tahsin Bozat
E-posta: tbozat@hotmail.com
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Yazar: Mehmet Melek
E-posta: mehmetmelek73@gmail.com
Kurum: Department of Cardiology, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Ülke: Turkey


Bibtex @araştırma makalesi { eurj262880, journal = {The European Research Journal}, issn = {}, address = {Sağlık Araştırmaları ve Stratejileri Derneği}, year = {2017}, volume = {3}, pages = {16 - 24}, doi = {10.18621/eurj.2016.5000200322}, title = {Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography}, language = {en}, key = {cite}, author = {Bozat, Tahsin and Oztas Cosar, Selvi and Ari, Selma and Celiloglu, Nuran and Emlek, Nadir and Melek, Mehmet and Doganay, Kubra and Ari, Hasan and Aydin, Cihan and Cetinkaya, Ahmet Seckin} }
APA Ari, H , Oztas Cosar, S , Ari, S , Doganay, K , Aydin, C , Emlek, N , Celiloglu, N , Cetinkaya, A , Bozat, T , Melek, M . (2017). Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography. The European Research Journal, 3 (1), 16-24. DOI: 10.18621/eurj.2016.5000200322
MLA Ari, H , Oztas Cosar, S , Ari, S , Doganay, K , Aydin, C , Emlek, N , Celiloglu, N , Cetinkaya, A , Bozat, T , Melek, M . "Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography". The European Research Journal 3 (2017): 16-24 <http://dergipark.gov.tr/eurj/issue/27747/262880>
Chicago Ari, H , Oztas Cosar, S , Ari, S , Doganay, K , Aydin, C , Emlek, N , Celiloglu, N , Cetinkaya, A , Bozat, T , Melek, M . "Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography". The European Research Journal 3 (2017): 16-24
RIS TY - JOUR T1 - Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography AU - Hasan Ari , Selvi Oztas Cosar , Selma Ari , Kubra Doganay , Cihan Aydin , Nadir Emlek , Nuran Celiloglu , Ahmet Seckin Cetinkaya , Tahsin Bozat , Mehmet Melek Y1 - 2017 PY - 2017 N1 - doi: 10.18621/eurj.2016.5000200322 DO - 10.18621/eurj.2016.5000200322 T2 - The European Research Journal JF - Journal JO - JOR SP - 16 EP - 24 VL - 3 IS - 1 SN - -2149-3189 M3 - doi: 10.18621/eurj.2016.5000200322 UR - http://dx.doi.org/10.18621/eurj.2016.5000200322 Y2 - 2016 ER -
EndNote %0 The European Research Journal Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography %A Hasan Ari , Selvi Oztas Cosar , Selma Ari , Kubra Doganay , Cihan Aydin , Nadir Emlek , Nuran Celiloglu , Ahmet Seckin Cetinkaya , Tahsin Bozat , Mehmet Melek %T Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography %D 2017 %J The European Research Journal %P -2149-3189 %V 3 %N 1 %R doi: 10.18621/eurj.2016.5000200322 %U 10.18621/eurj.2016.5000200322