Yıl 2018, Cilt 4, Sayı 1, Sayfalar 1 - 5 2018-01-04

Inflammation-related cancer or cancer-related inflammation

Shrihari T.G [1]

244 193

Inflammation is the body’s defensive action against various stimuli such as physical or chemical or infectious agents. Acute inflammation and their mediators help in tissue repair and healing. If the inflammation aggravates chronically, non-resolved, dysregulated immune system, results release of various inflammatory mediators such as free radicals (ROS and RNS), cytokines, chemokines, growth factors and proteolytic enzymes produced by innate and adaptive immune cells activate transcriptional factors (NF-KB,STAT3 and HIF-1α) results in cell proliferation, angiogenesis, immunosuppression, genetic instability, invasion and metastasis. Oncogenes related to cancer activate inflammatory mediators such as chemokines and cytokines, which alters the inflammatory tumor microenvironment, promotes tumor progression. This article highlights about the role of inflammation and oncogenes activate inflammatory mediators in tumor progression.

Inflammation,cancer,lymphocytes,NF-KB,STAT3,myeloid-derived suppressor cells,inflammatory mediators,tumor associated macrophages,tumor associated neutrophils,HIF-1α,oncogenes,cytokines,chemokines,growth factors,COX-2
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Konular Sağlık Bilimleri
Dergi Bölümü Reviews
Yazarlar

Yazar: Shrihari T.G
E-posta: drshrihariomr@gmail.com
Kurum: Department of Oral Medicine and Oral Oncology, Krishna Devaraya College of Dental Sciences and Hospital, Bangalore-562157, Karnata
Ülke: India


Bibtex @derleme { eurj312327, journal = {The European Research Journal}, issn = {}, address = {Sağlık Araştırmaları ve Stratejileri Derneği}, year = {2018}, volume = {4}, pages = {1 - 5}, doi = {10.18621/eurj.312327}, title = {Inflammation-related cancer or cancer-related inflammation}, key = {cite}, author = {T.G, Shrihari} }
APA T.G, S . (2018). Inflammation-related cancer or cancer-related inflammation. The European Research Journal, 4 (1), 1-5. DOI: 10.18621/eurj.312327
MLA T.G, S . "Inflammation-related cancer or cancer-related inflammation". The European Research Journal 4 (2018): 1-5 <http://dergipark.gov.tr/eurj/issue/32896/312327>
Chicago T.G, S . "Inflammation-related cancer or cancer-related inflammation". The European Research Journal 4 (2018): 1-5
RIS TY - JOUR T1 - Inflammation-related cancer or cancer-related inflammation AU - Shrihari T.G Y1 - 2018 PY - 2018 N1 - doi: 10.18621/eurj.312327 DO - 10.18621/eurj.312327 T2 - The European Research Journal JF - Journal JO - JOR SP - 1 EP - 5 VL - 4 IS - 1 SN - -2149-3189 M3 - doi: 10.18621/eurj.312327 UR - http://dx.doi.org/10.18621/eurj.312327 Y2 - 2017 ER -
EndNote %0 The European Research Journal Inflammation-related cancer or cancer-related inflammation %A Shrihari T.G %T Inflammation-related cancer or cancer-related inflammation %D 2018 %J The European Research Journal %P -2149-3189 %V 4 %N 1 %R doi: 10.18621/eurj.312327 %U 10.18621/eurj.312327