Yıl 2018, Cilt 4, Sayı 2, Sayfalar 112 - 117 2018-04-04

Sensitivity of localization studies performed by various radiologists in the evaluation of parathyroid lesions

Pınar Şişman [1] , Özen Öz Gül [2] , Soner Cander [3] , Ahmet Bilgehan Şahin [4] , Çoşkun Demirtaş [5] , Aybüke Muti [6] , Onur Elbasan [7] , Özlem Saraydaroğlu [8] , Erdinç Ertürk [9]

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Objectives. Preoperative imaging studies are commonly used in the diagnosis of primary hyperparathyroidism to increase the success rate of surgery. In the present study, we aimed to correlate surgical outcomes with the sensitivity of localization studies that were performed by various radiologists. Methods. One hundred eighty-nine patients with preoperative diagnosis primary hyperparathyroidism were included. A total of 174 patients in whom hypercalcemia had been cured by parathyroidectomy, were evaluated retrospectively. In total, 184 lesions were excised from these 174 patients. Ultrasonography (USG) and technetium-99m-methoxy isobutyl isonitrile (99mTc-MIBI) imaging yielded correctly localized lesion in 74 and 108 patients, respectively. Results. The specificity of USG and 99mTc-MIBI imaging were similar (95.9% and 95.0%, respectively). However, the sensitivity was not satisfactory (45.9% for USG, 62.4% for 99mTc-MIBI). The gland size was not significant for the rate of lesion detection by 99mTc-MIBI scan or USG. Significant differences were not observed between the preoperative serum parathormone, serum calcium or 24-hour urine calcium excretion levels and the success rate of localization with either USG or 99mTc-MIBI. Conclusions. Radiologist experience in ultrasonographic parathyroid imaging was found to affect sensitivity. Therefore, surgeons, radiologists and endocrinologists that perform ultrasonographic evaluation should have extensive experience. 

primary hyperparathyroidism, parathyroidectomy, localization studies, ultrasonography, technetium-99m-methoxy isobutyl isonitrile
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Dergi Bölümü Original Article
Yazarlar

Yazar: Pınar Şişman
E-posta: pinar.sisman@hotmail.com
Kurum: Department of Endocrinology and Metabolism, Harakani State Hospital, Kars
Ülke: Turkey


Yazar: Özen Öz Gül
E-posta: drozenoz@uludag.edu.tr
Kurum: Department of Endocrinology and Metabolism, Uludağ University School of Medicine, Bursa
Ülke: Turkey


Yazar: Soner Cander
E-posta: drcander@gmail.com
Kurum: Department of Endocrinology and Metabolism, Uludağ University School of Medicine, Bursa
Ülke: Turkey


Yazar: Ahmet Bilgehan Şahin
E-posta: absahin@uludag.edu.tr
Kurum: Department of Internal Medicine, Uludağ University School of Medicine, Bursa
Ülke: Turkey


Yazar: Çoşkun Demirtaş
E-posta: cdemirtas@uludag.edu.tr
Kurum: Department of Internal Medicine, Uludağ University School of Medicine, Bursa
Ülke: Turkey


Yazar: Aybüke Muti
E-posta: aybukemuti@gmail.com
Kurum: Department of Internal Medicine, Uludağ University School of Medicine, Bursa
Ülke: Turkey


Yazar: Onur Elbasan
E-posta: dronurelbasan@gmail.com
Kurum: Department of Internal Medicine, Uludağ University School of Medicine, Bursa
Ülke: Turkey


Yazar: Özlem Saraydaroğlu
E-posta: ozlemsaraydaroglu@uludag.edu.tr
Kurum: Department of Pathology, Uludağ University School of Medicine, Bursa
Ülke: Turkey


Yazar: Erdinç Ertürk
E-posta: ererturk@uludag.edu.tr
Kurum: Department of Endocrinology and Metabolism, Uludağ University School of Medicine, Bursa
Ülke: Turkey


Bibtex @araştırma makalesi { eurj308830, journal = {The European Research Journal}, issn = {}, address = {Sağlık Araştırmaları ve Stratejileri Derneği}, year = {2018}, volume = {4}, pages = {112 - 117}, doi = {10.18621/eurj.308830}, title = {Sensitivity of localization studies performed by various radiologists in the evaluation of parathyroid lesions}, key = {cite}, author = {Saraydaroğlu, Özlem and Öz Gül, Özen and Demirtaş, Çoşkun and Cander, Soner and Şişman, Pınar and Elbasan, Onur and Ertürk, Erdinç and Muti, Aybüke and Şahin, Ahmet Bilgehan} }
APA Şişman, P , Öz Gül, Ö , Cander, S , Şahin, A , Demirtaş, Ç , Muti, A , Elbasan, O , Saraydaroğlu, Ö , Ertürk, E . (2018). Sensitivity of localization studies performed by various radiologists in the evaluation of parathyroid lesions. The European Research Journal, 4 (2), 112-117. DOI: 10.18621/eurj.308830
MLA Şişman, P , Öz Gül, Ö , Cander, S , Şahin, A , Demirtaş, Ç , Muti, A , Elbasan, O , Saraydaroğlu, Ö , Ertürk, E . "Sensitivity of localization studies performed by various radiologists in the evaluation of parathyroid lesions". The European Research Journal 4 (2018): 112-117 <http://dergipark.gov.tr/eurj/issue/32986/308830>
Chicago Şişman, P , Öz Gül, Ö , Cander, S , Şahin, A , Demirtaş, Ç , Muti, A , Elbasan, O , Saraydaroğlu, Ö , Ertürk, E . "Sensitivity of localization studies performed by various radiologists in the evaluation of parathyroid lesions". The European Research Journal 4 (2018): 112-117
RIS TY - JOUR T1 - Sensitivity of localization studies performed by various radiologists in the evaluation of parathyroid lesions AU - Pınar Şişman , Özen Öz Gül , Soner Cander , Ahmet Bilgehan Şahin , Çoşkun Demirtaş , Aybüke Muti , Onur Elbasan , Özlem Saraydaroğlu , Erdinç Ertürk Y1 - 2018 PY - 2018 N1 - doi: 10.18621/eurj.308830 DO - 10.18621/eurj.308830 T2 - The European Research Journal JF - Journal JO - JOR SP - 112 EP - 117 VL - 4 IS - 2 SN - -2149-3189 M3 - doi: 10.18621/eurj.308830 UR - http://dx.doi.org/10.18621/eurj.308830 Y2 - 2017 ER -
EndNote %0 The European Research Journal Sensitivity of localization studies performed by various radiologists in the evaluation of parathyroid lesions %A Pınar Şişman , Özen Öz Gül , Soner Cander , Ahmet Bilgehan Şahin , Çoşkun Demirtaş , Aybüke Muti , Onur Elbasan , Özlem Saraydaroğlu , Erdinç Ertürk %T Sensitivity of localization studies performed by various radiologists in the evaluation of parathyroid lesions %D 2018 %J The European Research Journal %P -2149-3189 %V 4 %N 2 %R doi: 10.18621/eurj.308830 %U 10.18621/eurj.308830