Yıl 2018, Cilt 4, Sayı 4, Sayfalar 294 - 299 2018-10-04

Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema

Kuddusi Teberik [1] , Mehmet Tahir Eski [2] , Murat Kaya [3]

69 161

Objectives: To determine the correlation between central corneal thickness (CCT) and central macular thickness (CMT), and fasting plasma glucose levels and HbA1c levels before diabetic macular edema (DME) in type 2 diabetes mellitus (DM) patients without diabetic retinopathy.

Methods: Forty-four eyes of subjects diagnosed with type 2 DM, and 45 healthy control subjects participated in this study. Detailed ophthalmologic examination was performed with all participants. CMT was measured in both groups by Spectral-domain optical coherence tomography. CCT measurements were made with an Echoscan US-500 ultrasonic pachymeter. Blood biochemical tests for glycated hemoglobin (HbA1c) and fasting plasma glucose levels were run on all patients.

Results: The results of the study showed that the mean CCT was significantly thicker in type 2 DM patients 563.84 ± 33.25 μm than in the controls 550.13 ± 28.41 μm (p = 0.039). The mean of CMT was 231.27 ± 37.74 μm in the study group and 225.38 ± 38.33 μm in the control group (p > 0.05). No relationship was found between CCT and CMT and HbA1c level in the study and control groups.

Conclusions: The mean CCT was significantly thicker in type 2 DM patients without diabetic retinopathy than in the controls. The mean CMT is thicker in type 2 DM patients without diabetic retinopathy patients than in the controls, but this difference was not statistically significant. Optical coherence tomography can be a perfect detector for early detection of DME. 

Diabetic macular edema, HbA1c, fasting plasma glucose levels, central corneal thickness, central macular thickness
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Konular Sağlık Bilimleri
Dergi Bölümü Original Article
Yazarlar

Orcid: 0000-0003-3141-0531
Yazar: Kuddusi Teberik (Sorumlu Yazar)
Kurum: Department of Ophthalmology, Düzce University School of Medicine, Düzce
Ülke: Turkey


Yazar: Mehmet Tahir Eski
Kurum: Department of Ophthalmology, Düzce University School of Medicine, Düzce
Ülke: Turkey


Yazar: Murat Kaya
Kurum: Department of Ophthalmology, Düzce University School of Medicine, Düzce
Ülke: Turkey


Bibtex @araştırma makalesi { eurj362263, journal = {The European Research Journal}, issn = {}, eissn = {2149-3189}, address = {Sağlık Araştırmaları ve Stratejileri Derneği}, year = {2018}, volume = {4}, pages = {294 - 299}, doi = {10.18621/eurj.362263}, title = {Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema}, key = {cite}, author = {Kaya, Murat and Eski, Mehmet Tahir and Teberik, Kuddusi} }
APA Teberik, K , Eski, M , Kaya, M . (2018). Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema. The European Research Journal, 4 (4), 294-299. DOI: 10.18621/eurj.362263
MLA Teberik, K , Eski, M , Kaya, M . "Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema". The European Research Journal 4 (2018): 294-299 <http://dergipark.gov.tr/eurj/issue/32988/362263>
Chicago Teberik, K , Eski, M , Kaya, M . "Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema". The European Research Journal 4 (2018): 294-299
RIS TY - JOUR T1 - Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema AU - Kuddusi Teberik , Mehmet Tahir Eski , Murat Kaya Y1 - 2018 PY - 2018 N1 - doi: 10.18621/eurj.362263 DO - 10.18621/eurj.362263 T2 - The European Research Journal JF - Journal JO - JOR SP - 294 EP - 299 VL - 4 IS - 4 SN - -2149-3189 M3 - doi: 10.18621/eurj.362263 UR - http://dx.doi.org/10.18621/eurj.362263 Y2 - 2017 ER -
EndNote %0 The European Research Journal Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema %A Kuddusi Teberik , Mehmet Tahir Eski , Murat Kaya %T Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema %D 2018 %J The European Research Journal %P -2149-3189 %V 4 %N 4 %R doi: 10.18621/eurj.362263 %U 10.18621/eurj.362263
ISNAD Teberik, Kuddusi , Eski, Mehmet Tahir , Kaya, Murat . "Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema". The European Research Journal 4 / 4 (Ekim 2018): 294-299. http://dx.doi.org/10.18621/eurj.362263