Yıl 2019, Cilt 5, Sayı 2, Sayfalar 413 - 417 2019-03-04

An interesting co-existence of celiac disease and idiopathic pulmonary hemosiderosis: Lane Hamilton syndrome

Gökçe Pınar Reis [1] , Ali Fettah [2] , Burcu Volkan [3] , Sevilay Özmen [4] , İlknur Çalık [5] , Alev Cansu Certel [6]

66 213

Idiopathic pulmonary hemosiderosis is characterized by hemoptysis resulting from recurring alveolar hemorrhage attacks, iron deficiency anemia, and parenchymal infiltrations as seen on chest radiographs. The clinical course may consist of silent and asymptomatic attacks, or it may sometimes exhibit a fulminant course with rapidly developing anemia and hypoxemia. Celiac disease is an autoimmune enteropathy triggered by the consumption of gluten-containing foods in genetically predisposed individuals. Co-existence of idiopathic pulmonary hemosiderosis and celiac disease is defined as Lane-Hamilton syndrome. We describe a case of Lane-Hamilton syndrome with growth and developmental delay; complete remission of pulmonary symptoms was achieved with a gluten-free diet. 

Idiopathic pulmonary hemosiderosis, celiac disease, anemia, gluten-free diet
  • [1] Nishino M, Patrick James L, Connors Jean M. Lane-Hamilton Syndrome. Radiology 2010;254:985-8.
  • [2] Loule S, Russell LA, Richeson RB, Carroll E. Circulating immune complexes with pulmonary hemorrhage during pregnancy in idiopathic pulmonary hemosiderosis. Chest 1993;104:1907-9.
  • [3] Leaker B, Cambridge G, du Bois RM, Neild GH. Idiopathic pulmonary haemosiderosis: a form of microscopic polyarteritis? Thorax 1992;47:988-90.
  • [4] Khemiri M, Ouederni M, Khaldi M, Barsaoui S. Screening for celiac disease in idiopathic pulmonary hemosiderosis. Gastroenterol Clin Biol 2008; 32:745-8.
  • [5] Ferrari GF, Fioretta JR, Alves AFR, Brandao GS. Idiopathic pulmonary haemosiderosis: case report. J Pediatr 2006;76:149-52.
  • [6] Ioachimescu O.C, Sieber S, Kotch A. Idiopathic pulmonary hemosiderosis revisited. Eur Respir J 2004;24:162-70.
  • [7] Margon P.G, Tuner Warwick M. Pulmonary hemosiderosis and pulmonary haemorrhage. Br Dis Chest 1981;75:225-42.
  • [8] Ertekin V, Selimoglu MA, Gursan N, Ozkan B. Idiopathic pulmonary hemosiderozis in children with celiac disease. Respir Med 2006;100:568-9.
  • [9] Le Clainche L, Le Bourgeois M, Fauroux B, Forenza N, Dommergues JP, Desbois JC, et al. Long-term outcome of idiopathic pulmonary hemosiderosis in children. Medicine (Baltimore) 2000;79:318-26.
  • [10] Corrin B, Jagusch M, Dewar A, Tungekar MF, Davies DR, Warner JO, et al. Fine structural changes in idiopathic pulmonary haemosiderosis. J Pathol 1987;153:249-56.
  • [11] Milman N, Pedersen FM. Idiopathic pulmonary hemosiderozis. Epidemiology, pathogenic aspects and diagnosis. Respir Med 1998;92:902-7.
  • [12] Custer G, Balcerzak S, Rinehart J. Human macrophage hemoglobin-iron metabolism in vitro. Am J Hematol 1982;13:23-36.
  • [13] Erdil A, Ateş Y. Gluten enteropatisinde son gelişmeler. Güncel Gastroenteroloji 2005;9:18-28.
  • [14] Fesus L, Piacentini M. Transglutaminase 2: an enigmatic enzyme with diverse functions. Trends Biochem Sci 2002;27:534-9.
  • [15] Perelman S, Dupuy C, Bourrillon A. [The associationof pulmonary hemosiderosis and celiac disease. Apropo of a new case in a child]. Ann Pediatr 1992;39:185-8. [Article in French]
  • [16] Bakan DN, Kanmaz D, Özkan G, Uçar E, Taşçı C, Karslıoğlu Y, et al. [Idiopathic pulmonary hemosiderosis]. Tur Toraks Der 2008;9:124-6. [Article in Turkish]
Birincil Dil en
Konular Sağlık Bilimleri ve Hizmetleri
Dergi Bölümü Case Report
Yazarlar

Orcid: 0000-0002-0064-2711
Yazar: Gökçe Pınar Reis
Kurum: Department of Pediatric Hematology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey
Ülke: Turkey


Orcid: 0000-0003-4109-2143
Yazar: Ali Fettah
Kurum: Department of Pediatric Hematology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey
Ülke: Turkey


Orcid: 0000-0002-0528-3826
Yazar: Burcu Volkan (Sorumlu Yazar)
Kurum: Department of Pediatric Gastroenterology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey
Ülke: Turkey


Orcid: 0000-0002-1973-6101
Yazar: Sevilay Özmen
Kurum: Department of Pathology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey
Ülke: Turkey


Orcid: 0000-0003-2160-7453
Yazar: İlknur Çalık
Kurum: Department of Pathology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey
Ülke: Turkey


Orcid: 0000-0002-1096-3455
Yazar: Alev Cansu Certel
Kurum: Department of Pediatrics, Erzurum Regional Training and Research Hospital, Erzurum, Turkey
Ülke: Turkey


Bibtex @olgu sunumu { eurj406178, journal = {The European Research Journal}, issn = {}, eissn = {2149-3189}, address = {Sağlık Araştırmaları ve Stratejileri Derneği}, year = {2019}, volume = {5}, pages = {413 - 417}, doi = {10.18621/eurj.406178}, title = {An interesting co-existence of celiac disease and idiopathic pulmonary hemosiderosis: Lane Hamilton syndrome}, key = {cite}, author = {Reis, Gökçe Pınar and Fettah, Ali and Volkan, Burcu and Özmen, Sevilay and Çalık, İlknur and Certel, Alev Cansu} }
APA Reis, G , Fettah, A , Volkan, B , Özmen, S , Çalık, İ , Certel, A . (2019). An interesting co-existence of celiac disease and idiopathic pulmonary hemosiderosis: Lane Hamilton syndrome. The European Research Journal, 5 (2), 413-417. DOI: 10.18621/eurj.406178
MLA Reis, G , Fettah, A , Volkan, B , Özmen, S , Çalık, İ , Certel, A . "An interesting co-existence of celiac disease and idiopathic pulmonary hemosiderosis: Lane Hamilton syndrome". The European Research Journal 5 (2019): 413-417 <http://dergipark.gov.tr/eurj/issue/41339/406178>
Chicago Reis, G , Fettah, A , Volkan, B , Özmen, S , Çalık, İ , Certel, A . "An interesting co-existence of celiac disease and idiopathic pulmonary hemosiderosis: Lane Hamilton syndrome". The European Research Journal 5 (2019): 413-417
RIS TY - JOUR T1 - An interesting co-existence of celiac disease and idiopathic pulmonary hemosiderosis: Lane Hamilton syndrome AU - Gökçe Pınar Reis , Ali Fettah , Burcu Volkan , Sevilay Özmen , İlknur Çalık , Alev Cansu Certel Y1 - 2019 PY - 2019 N1 - doi: 10.18621/eurj.406178 DO - 10.18621/eurj.406178 T2 - The European Research Journal JF - Journal JO - JOR SP - 413 EP - 417 VL - 5 IS - 2 SN - -2149-3189 M3 - doi: 10.18621/eurj.406178 UR - http://dx.doi.org/10.18621/eurj.406178 Y2 - 2018 ER -
EndNote %0 The European Research Journal An interesting co-existence of celiac disease and idiopathic pulmonary hemosiderosis: Lane Hamilton syndrome %A Gökçe Pınar Reis , Ali Fettah , Burcu Volkan , Sevilay Özmen , İlknur Çalık , Alev Cansu Certel %T An interesting co-existence of celiac disease and idiopathic pulmonary hemosiderosis: Lane Hamilton syndrome %D 2019 %J The European Research Journal %P -2149-3189 %V 5 %N 2 %R doi: 10.18621/eurj.406178 %U 10.18621/eurj.406178
ISNAD Reis, Gökçe Pınar , Fettah, Ali , Volkan, Burcu , Özmen, Sevilay , Çalık, İlknur , Certel, Alev Cansu . "An interesting co-existence of celiac disease and idiopathic pulmonary hemosiderosis: Lane Hamilton syndrome". The European Research Journal 5 / 2 (Mart 2019): 413-417. http://dx.doi.org/10.18621/eurj.406178