Year 2019, Volume 5, Issue 3, Pages 515 - 521 2019-05-04

Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels

Hande Peynirci [1] , Canan Ersoy [2] , Vildan Gürsoy [3] , Ayten Girgin [4] , Mehmet Ali Aşık [5] , Ahmet Gültepe [6] , Güven Özkaya [7] , Emel Isıktas Sayılar [8] , Alpaslan Ersoy [9]

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Objectives: Although bone biopsy is considered the gold standard for the definitive diagnosis of renal osteodystrophy; it is not suitable for routine clinical practice due to its invasive nature. The present study was aimed to evaluate and compare the bone mineral status using dual energy X-ray absorptiometry of patients with or without chronic kidney disease in young population with elevated parathyroid hormone levels.

Methods: This was a single center, cross-sectional, retrospective study conducted in patients younger than 45 years of age. The study was performed in the outpatient clinic of a university hospital. Patients with elevated parathyroid hormone levels were included.

Results: Among them, 29 had renal insufficiency, 158 had normal renal function. Measured bone mineral density with dual energy X-ray absorptiometry and laboratory values were collected from patient files. The primary end point was to assess the efficiacy of dual energy X-ray absorptiometry in patients with or without renal failure. Except Z score at Ward’s triangle, all of the T and Z scores at lomber, femur neck, trochanteric, and intertrochanteric areas were found significantly lower in patients with chronic kidney disease compared to those without (p < 0.001).

Conclusion: Dual energy X-ray absorptiometry seemed to be a reliable method for detection of osteoporosis in premenopausal female and male patients younger than 45 years of age with or without renal failure with elevated parathyroid hormone levels. 

hyperparathyroidism, renal insufficiency, osteoporosis, dual energy X-ray absorptiometry
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Primary Language en
Subjects Health Care Sciences and Services
Journal Section Original Articles
Authors

Orcid: 0000-0003-2631-8853
Author: Hande Peynirci (Primary Author)
Institution: Department of Internal Medicine, Division of Endocrinology and Metabolism, Kanuni Sultan Süleyman Training and Research Hospital, İstanbul, Turkey
Country: Turkey


Orcid: 0000-0003-4510-6282
Author: Canan Ersoy
Institution: Department of Internal Medicine, Division of Endocrinology and Metabolism, Uludağ University School of Medicine, Bursa, Turkey
Country: Turkey


Orcid: 0000-0002-3645-9345
Author: Vildan Gürsoy
Institution: Department of Internal Medicine, Uludağ University School of Medicine, Bursa, Turkey
Country: Turkey


Orcid: 0000-0002-2176-1912
Author: Ayten Girgin
Institution: Department of Internal Medicine, Uludağ University School of Medicine, Bursa, Turkey
Country: Turkey


Orcid: 0000-0002-1631-6080
Author: Mehmet Ali Aşık
Institution: Department of Internal Medicine, Uludağ University School of Medicine, Bursa, Turkey
Country: Turkey


Orcid: 0000-0001-7312-9137
Author: Ahmet Gültepe
Institution: Department of Internal Medicine, Uludağ University School of Medicine, Bursa, Turkey
Country: Turkey


Orcid: 0000-0003-0297-846X
Author: Güven Özkaya
Institution: Department of Statistics, Uludağ University School of Medicine, Bursa, Turkey
Country: Turkey


Orcid: 0000-0002-8824-6560
Author: Emel Isıktas Sayılar
Institution: Department of Internal Medicine, Division of Nephrology, Edirne State Hospital, Edirne, Turkey
Country: Turkey


Orcid: 0000-0002-0710-0923
Author: Alpaslan Ersoy
Institution: Department of Internal Medicine, Division of Nephrology, Uludağ University School of Medicine, Bursa, Turkey
Country: Turkey


Bibtex @research article { eurj378720, journal = {The European Research Journal}, issn = {}, eissn = {2149-3189}, address = {The Association of Health Research and Strategy}, year = {2019}, volume = {5}, pages = {515 - 521}, doi = {10.18621/eurj.378720}, title = {Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels}, key = {cite}, author = {Peynirci, Hande and Ersoy, Canan and Gürsoy, Vildan and Girgin, Ayten and Aşık, Mehmet Ali and Gültepe, Ahmet and Özkaya, Güven and Isıktas Sayılar, Emel and Ersoy, Alpaslan} }
APA Peynirci, H , Ersoy, C , Gürsoy, V , Girgin, A , Aşık, M , Gültepe, A , Özkaya, G , Isıktas Sayılar, E , Ersoy, A . (2019). Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels. The European Research Journal, 5 (3), 515-521. DOI: 10.18621/eurj.378720
MLA Peynirci, H , Ersoy, C , Gürsoy, V , Girgin, A , Aşık, M , Gültepe, A , Özkaya, G , Isıktas Sayılar, E , Ersoy, A . "Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels". The European Research Journal 5 (2019): 515-521 <http://dergipark.gov.tr/eurj/issue/42399/378720>
Chicago Peynirci, H , Ersoy, C , Gürsoy, V , Girgin, A , Aşık, M , Gültepe, A , Özkaya, G , Isıktas Sayılar, E , Ersoy, A . "Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels". The European Research Journal 5 (2019): 515-521
RIS TY - JOUR T1 - Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels AU - Hande Peynirci , Canan Ersoy , Vildan Gürsoy , Ayten Girgin , Mehmet Ali Aşık , Ahmet Gültepe , Güven Özkaya , Emel Isıktas Sayılar , Alpaslan Ersoy Y1 - 2019 PY - 2019 N1 - doi: 10.18621/eurj.378720 DO - 10.18621/eurj.378720 T2 - The European Research Journal JF - Journal JO - JOR SP - 515 EP - 521 VL - 5 IS - 3 SN - -2149-3189 M3 - doi: 10.18621/eurj.378720 UR - https://doi.org/10.18621/eurj.378720 Y2 - 2018 ER -
EndNote %0 The European Research Journal Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels %A Hande Peynirci , Canan Ersoy , Vildan Gürsoy , Ayten Girgin , Mehmet Ali Aşık , Ahmet Gültepe , Güven Özkaya , Emel Isıktas Sayılar , Alpaslan Ersoy %T Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels %D 2019 %J The European Research Journal %P -2149-3189 %V 5 %N 3 %R doi: 10.18621/eurj.378720 %U 10.18621/eurj.378720
ISNAD Peynirci, Hande , Ersoy, Canan , Gürsoy, Vildan , Girgin, Ayten , Aşık, Mehmet Ali , Gültepe, Ahmet , Özkaya, Güven , Isıktas Sayılar, Emel , Ersoy, Alpaslan . "Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels". The European Research Journal 5 / 3 (May 2019): 515-521. https://doi.org/10.18621/eurj.378720