Year 2018, Volume 43, Issue 6, Pages 943 - 956 2018-11-01

ROLE OF PROBIOTICS IN Helicobacter pylori INFECTION
Helicobacter pylori ENFEKSİYONUNDA PROBİYOTİKLERİN ROLÜ

Vildan Akdeniz [1] , A. Sibel Akalın [2] , Elif Özer [3]

203 256

Helicobacter pylori infection which is recognized as carcinogen by WHO is a major public health problem in both developing and developed countries with high prevalence. It is well known that H. pylori causes mainly to chronic gastritis colonising in the gastric mucosa. Gastric microbiota is important in the occurrence and development of diseases caused by H. pylori. Nutritional modification providing a reduction in the population of H. pylori at the gastric mucosa will help to decrease the risk of H. pylori-associated diseases including peptic ulcer, chronic gastritis, gastric adenocarcinoma, mucosa associated lymphoid tissue lymphoma and duodenal ulcer disease. Antibiotic therapy is applied in this infection, but meanwhile it’s side effects and antibiotic resistance be seen. Studies indicate that probiotics which have positive effects on intestinal microbiota increase eradication rates of H. pylori, improve patient clinical symptoms and improve patient compliance by reducing side effects associated with antibiotic treatment.

Dünya Sağlık Örgütü tarafından kanserojen grupta sınıflandırılan Helicobacter pylori enfeksiyonu yüksek tekrarlanma sıklığı ile hem gelişmekte olan hem de gelişmiş ülkelerde görülen önemli bir halk sağlığı sorunudur. H. pylori'nin mide mukozasında kolonize olarak kronik gastritin ana nedenini oluşturduğu bilinmektedir. Mide mikrobiyotası H. pylori’nin sebep olduğu hastalıkların oluşmasında ve gelişmesinde önemli bir rol oynamaktadır. Beslenme düzenindeki değişimlerle gastrik mukozadaki H. pylori yoğunluğunda azalma sağlanması, H. pylori ile ilişkili peptik ülser, kronik gastrit, mide adenokarsinoması, mukoza ile ilişkili lenfoid doku lenfoması ve duodenal ülser hastalığı gibi hastalıkların ortaya çıkma riskini azaltmaya yardımcı olacaktır. H. pylori enfeksiyonunda antibiyotik tedavisi uygulanmakta, fakat bu süreçte antibiyotik direnci ve antibiyotik tedavisinin yan etkileri görülebilmektedir. Yapılan çalışmalar bağırsak mikrobiyotası üzerinde olumlu etkiye sahip olan probiyotiklerin; H. pylori enfeksiyonu tedavisinde eradikasyon oranını arttırdığını, hasta klinik belirtilerini iyileştirdiğini ve tedaviye bağlı antibiyotik ile ilişkili yan etkileri azaltarak hasta uyumunu arttırdığını belirtmektedir.  

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Primary Language tr
Subjects Science
Published Date 2018
Journal Section Articles
Authors

Orcid: 0000-0002-2288-7832
Author: Vildan Akdeniz (Primary Author)
Institution: Ege Üniversitesi, Ziraat Fakültesi, Süt Teknolojisi Bölümü
Country: Turkey


Author: A. Sibel Akalın
Institution: Ege Üniversitesi, Ziraat Fakültesi, Süt Teknolojisi Bölümü

Author: Elif Özer
Institution: Ege Üniversitesi, Ziraat Fakültesi, Süt Teknolojisi Bölümü

Bibtex @review { gida433676, journal = {GIDA}, issn = {1300-3070}, eissn = {1309-6273}, address = {Gıda Teknolojisi Derneği}, year = {2018}, volume = {43}, pages = {943 - 956}, doi = {10.15237/gida.GD18062}, title = {Helicobacter pylori ENFEKSİYONUNDA PROBİYOTİKLERİN ROLÜ}, key = {cite}, author = {Akdeniz, Vildan and Akalın, A. Sibel and Özer, Elif} }
APA Akdeniz, V , Akalın, A , Özer, E . (2018). Helicobacter pylori ENFEKSİYONUNDA PROBİYOTİKLERİN ROLÜ. GIDA, 43 (6), 943-956. DOI: 10.15237/gida.GD18062
MLA Akdeniz, V , Akalın, A , Özer, E . "Helicobacter pylori ENFEKSİYONUNDA PROBİYOTİKLERİN ROLÜ". GIDA 43 (2018): 943-956 <http://dergipark.gov.tr/gida/issue/39712/433676>
Chicago Akdeniz, V , Akalın, A , Özer, E . "Helicobacter pylori ENFEKSİYONUNDA PROBİYOTİKLERİN ROLÜ". GIDA 43 (2018): 943-956
RIS TY - JOUR T1 - Helicobacter pylori ENFEKSİYONUNDA PROBİYOTİKLERİN ROLÜ AU - Vildan Akdeniz , A. Sibel Akalın , Elif Özer Y1 - 2018 PY - 2018 N1 - doi: 10.15237/gida.GD18062 DO - 10.15237/gida.GD18062 T2 - GIDA JF - Journal JO - JOR SP - 943 EP - 956 VL - 43 IS - 6 SN - 1300-3070-1309-6273 M3 - doi: 10.15237/gida.GD18062 UR - https://doi.org/10.15237/gida.GD18062 Y2 - 2018 ER -
EndNote %0 THE JOURNAL OF FOOD Helicobacter pylori ENFEKSİYONUNDA PROBİYOTİKLERİN ROLÜ %A Vildan Akdeniz , A. Sibel Akalın , Elif Özer %T Helicobacter pylori ENFEKSİYONUNDA PROBİYOTİKLERİN ROLÜ %D 2018 %J GIDA %P 1300-3070-1309-6273 %V 43 %N 6 %R doi: 10.15237/gida.GD18062 %U 10.15237/gida.GD18062
ISNAD Akdeniz, Vildan , Akalın, A. Sibel , Özer, Elif . "Helicobacter pylori ENFEKSİYONUNDA PROBİYOTİKLERİN ROLÜ". GIDA 43 / 6 (November 2018): 943-956. https://doi.org/10.15237/gida.GD18062