Yıl 2018, Cilt 4, Sayı 3, Sayfalar 157 - 167 2018-12-24

Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review
Candida Mikroorganizmalarının Polimerik Yüzeylere Yapışmasının İncelenmesi

Hakan Kır [1] , İkrime Orkan Uçar [2] , Özge Kılınçel [3] , Emel Çalışkan [4]

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Microorganism adhesion on a material surface plays a crucial role on the application of biomedical devices, implants, drug delivery systems, scaffolds and so on. Desirable surfaces which have bioactive, bioinert or anti-biofoul property can be prepared by physical adsorption of specific compounds on these surfaces or chemical modification. Micro/nano patterned surface fabrication is one of the most important ways of surface modification. Studies reveal that surface properties such as wettability (hydrophilicity/hydrophobicity) character of a surface, surface charge, surface free energy, and surface roughness effects the adhesion of the microorganisms on material surfaces.


The aim of this study is the investigation of relationship between surface properties of polymeric materials and adhesion of Candida microorganisms who known as opportunist pathogens in medical area and the main reason of the systemic fungal infections.

Bir malzeme yüzeyi üzerindeki mikroorganizma adezyonu biyomedikal cihazlar, implantlar, ilaç salım sistemleri, yapı iskeleleri v.b. uygulamalarda kritik önem taşır. Biyoaktif, biyoinert, biyolojik kirlenmeyi önleyici özelliklere sahip olması istenen yüzeyler, spesifik bileşiklerin bu yüzeyler üzerine fiziksel adsorpsiyonu  ya da kimyasal modifikasyon ile hazırlanabilirler. Mikro/nano desenli yüzey üretimi yüzey modifikasyon yollarının en önemli olanlarından biridir. Çalışmalar ıslatılabilirlik (hidrofilisite/hidrofobisite), bir yüzeyin karakteri, yüzey yükü, serbest yüzey enerjisi ve yüzey pürüzlülüğü gibi yüzey özelliklerinin malzeme yüzeylerine olan mikroorganizma adezyonunu etkilediğini ortaya koymaktadır.


Bu çalışmanın amacı polimerik materyallerin yüzey özellikleri ile medikal alanda fırsatçı patojenler olarakta bilinen ve sistemik mantar enfeksiyonlarının başlıca sebebi olan Candida mikroorganizmalarının adezyonu arasındaki ilişkiyi incelemektir.

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Birincil Dil en
Konular Mühendislik, Kimya
Dergi Bölümü Konferans Bildirisi

Orcid: 0000-0002-6330-1666
Yazar: Hakan Kır
Ülke: Turkey

Orcid: 0000-0003-4026-1830
Yazar: İkrime Orkan Uçar (Sorumlu Yazar)
Ülke: Turkey

Orcid: 0000-0003-1872-6670
Yazar: Özge Kılınçel
Ülke: Turkey

Orcid: 0000-0002-9451-7865
Yazar: Emel Çalışkan
Ülke: Turkey

Bibtex @konferans bildirisi { gmbd427557, journal = {Gazi Mühendislik Bilimleri Dergisi (GMBD)}, issn = {2149-4916}, eissn = {2149-9373}, address = {Aydın KARAPINAR}, year = {2018}, volume = {4}, pages = {157 - 167}, doi = {}, title = {Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review}, key = {cite}, author = {Orkan Uçar, İkrime and Kılınçel, Özge and Kır, Hakan and Çalışkan, Emel} }
APA Kır, H , Orkan Uçar, İ , Kılınçel, Ö , Çalışkan, E . (2018). Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review. Gazi Mühendislik Bilimleri Dergisi (GMBD), 4 (3), 157-167. Retrieved from http://dergipark.gov.tr/gmbd/issue/41439/427557
MLA Kır, H , Orkan Uçar, İ , Kılınçel, Ö , Çalışkan, E . "Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review". Gazi Mühendislik Bilimleri Dergisi (GMBD) 4 (2018): 157-167 <http://dergipark.gov.tr/gmbd/issue/41439/427557>
Chicago Kır, H , Orkan Uçar, İ , Kılınçel, Ö , Çalışkan, E . "Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review". Gazi Mühendislik Bilimleri Dergisi (GMBD) 4 (2018): 157-167
RIS TY - JOUR T1 - Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review AU - Hakan Kır , İkrime Orkan Uçar , Özge Kılınçel , Emel Çalışkan Y1 - 2018 PY - 2018 N1 - DO - T2 - Gazi Mühendislik Bilimleri Dergisi (GMBD) JF - Journal JO - JOR SP - 157 EP - 167 VL - 4 IS - 3 SN - 2149-4916-2149-9373 M3 - UR - Y2 - 2018 ER -
EndNote %0 Gazi Mühendislik Bilimleri Dergisi (GMBD) Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review %A Hakan Kır , İkrime Orkan Uçar , Özge Kılınçel , Emel Çalışkan %T Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review %D 2018 %J Gazi Mühendislik Bilimleri Dergisi (GMBD) %P 2149-4916-2149-9373 %V 4 %N 3 %R %U
ISNAD Kır, Hakan , Orkan Uçar, İkrime , Kılınçel, Özge , Çalışkan, Emel . "Candida Mikroorganizmalarının Polimerik Yüzeylere Yapışmasının İncelenmesi". Gazi Mühendislik Bilimleri Dergisi (GMBD) 4 / 3 (Aralık 2018): 157-167.