Year 2015, Volume 5, Issue 4, Pages 226 - 233 2016-02-21

FREQUENCY OF HYPERCALCIURIA IN 4 TO 15 YEAR OLD CHILDREN
4-15 YAŞ ARASI ÇOCUKLARDA HİPERKALSİÜRİ SIKLIĞI

Ali GÜL [1] , İnci ARIKAN [2]

245 441

Objective: Idiopathic hypercalciuria ( IHC ) is very frequently seen metabolic disorder in children and causes to some symptoms as hematuria, disuria, enuresis, cholic pain and growth retardation. IHC is generally ended with urolithiasis ( 1-2 ). In this researh , we aim to notice frequency and clinically importance of hypercalciuria.

                Method: In pediatric polyclinic, 4 to 15 year old children detected for hypercalciuria by calcium, creatinine, sodium and potasium measuring in spot urine samples. we calculated the urine calcium creatinine ratio( Uca/Ucr ) and 0,20 and above accepted hypercalciuria ( 3 ). Urinary tract symptoms were recorded.

                Results: We studied 223 children in our pediatric polyclinic with an age range of 4 to 15 years (mean= 8.7 ±3,18.7 ±3,1).  124 ( %55.6) chidren were female and 99 ( %44.4 ) were male. In study group,  we found urine calcium creatinine  ratio  0,20 and above in 32 (%14.3 ). The prevalance was %18.2 in males and in females was  %11.3. 92(%41.3) children were have urinary system symptoms and hypercaluria was found in 25( %27.2 ) from these 92 symptomatic children. Of all hypercalciuric 32 children, 25( %78.1 ) children were symptomatic and the most frequently symptoms was abdominal pain with %68.8 frequency ( 22 children ). However in nonhypercaiuric 191 children abdominal pain was found 47( %24.6 ) children, from hypercalciuric children 22( %68,8 ) patients had abdominal pain ( p<0,001). The mean sodium creatinine ratio, in hypercalciuric children was 3,71±3,62 and in nonhypercaiuric was 1,70±1,28 (p<0,001).

                Conclusions: Because of the IHC frequently ended in urolithiasis, especially in urinary tract sympomatic children Uca/Ucr should be studied that is not invasive test and patients with IHC can be treated firstly with sodium restricted and potasium richly diets.

                     GİRİŞ VE AMAÇ: İdyopatik Hiperkalsiüri ( İHK ) çocuklarda sık görülen bir metabolik bozukluktur.  Hematuri, dizüri, enürezis, kolik ve büyüme  geriliği gibi semptomlara sebep olur ve genellikle ürolitiazisle sonuçlanır    ( 1,2 ). İHK klinik belirtileri ve sıklığına dikkat çekmek amacıyla bu çalışma yapıldı.

                YÖNTEM : Polikliniğe başvuran 4-15 yaş arası 223  çocukta spot idrarda kalsium, kreatinin, sodyum, potasyum incelendi. İdrarda kalsiyum kreatinin oranı (İkakr ) hesaplandı, 0.20 ve üzeri hiperkalsiüri olarak kabul edildi (3 ). Hastaların şikayetleri kaydedildi.

                BULGULAR : 4-15 yaş arası 223 hastanın 124( %55.6 )’ ü kız, 99( %44.4 )’ u erkekti. Yaş ortalaması ise 8.7 ±3,1’ di. 223 hastanın 32 ( %14.3 ) ’sinde İkakr  0.20’ in üzerindeydi. Erkeklerdeki prevalans %18.2 iken kızlarda %11.3’ tü. 223 hastanın 92(%41.3)’ sinde idrar semptomu vardı. İdrar semptomu olan 92 hastanın 25( %27.2 )’ inde hiperkalsiüri tespit edildi. Hiperkalsiürili 25( %78.1 ) hasta semptomatikti, en sık rastlanan semptom %68.8( 22 hasta ) ile karın ağrısıydı. İHK olmayan 191 hastanın 47( %24.6 )’ inde karın ağrısı varken, İHK olan 32 hastanın 22( %68,8 )’ sinde karın ağrısı vardı. Hiperkalsiürili olan vakalarda karın ağrısı görülme sıklığı daha fazlaydı ( p<0,001 ). İHK olanlarda sodyumun kreatinine oran ortalaması 3,71±3,62’ di. Diğer grupta ise sodyumun kreatinine oran ortalaması 1,70±1,28’ di. İHK olan vakalarda sodyum atılımı daha fazlaydı ( p<0,001 ).

                SONUÇ: İHK ürolitiazis için en önemli risk faktörü olmasından, özellikle üriner sistem semptomları olan çocuklarda idrarda İkakr  gibi  invazif olmayan bir tetkikle taranmalı ve tedavisinde başlangıçta sodyumdan fakir potasyumdan zengin diyet denenebilir.

               

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Primary Language en
Subjects
Journal Section Original Research
Authors

Author: Ali GÜL

Author: İnci ARIKAN

Bibtex @ { gopctd265845, journal = {Çağdaş Tıp Dergisi}, issn = {}, eissn = {2146-6009}, address = {Selcuk University}, year = {2016}, volume = {5}, pages = {226 - 233}, doi = {10.16899/ctd.32012}, title = {FREQUENCY OF HYPERCALCIURIA IN 4 TO 15 YEAR OLD CHILDREN}, key = {cite}, author = {GÜL, Ali and ARIKAN, İnci} }
APA GÜL, A , ARIKAN, İ . (2016). FREQUENCY OF HYPERCALCIURIA IN 4 TO 15 YEAR OLD CHILDREN. Çağdaş Tıp Dergisi, 5 (4), 226-233. Retrieved from http://dergipark.gov.tr/gopctd/issue/25166/265845
MLA GÜL, A , ARIKAN, İ . "FREQUENCY OF HYPERCALCIURIA IN 4 TO 15 YEAR OLD CHILDREN". Çağdaş Tıp Dergisi 5 (2016): 226-233 <http://dergipark.gov.tr/gopctd/issue/25166/265845>
Chicago GÜL, A , ARIKAN, İ . "FREQUENCY OF HYPERCALCIURIA IN 4 TO 15 YEAR OLD CHILDREN". Çağdaş Tıp Dergisi 5 (2016): 226-233
RIS TY - JOUR T1 - FREQUENCY OF HYPERCALCIURIA IN 4 TO 15 YEAR OLD CHILDREN AU - Ali GÜL , İnci ARIKAN Y1 - 2016 PY - 2016 N1 - DO - T2 - Çağdaş Tıp Dergisi JF - Journal JO - JOR SP - 226 EP - 233 VL - 5 IS - 4 SN - -2146-6009 M3 - UR - Y2 - 2019 ER -
EndNote %0 Çağdaş Tıp Dergisi FREQUENCY OF HYPERCALCIURIA IN 4 TO 15 YEAR OLD CHILDREN %A Ali GÜL , İnci ARIKAN %T FREQUENCY OF HYPERCALCIURIA IN 4 TO 15 YEAR OLD CHILDREN %D 2016 %J Çağdaş Tıp Dergisi %P -2146-6009 %V 5 %N 4 %R %U
ISNAD GÜL, Ali , ARIKAN, İnci . "FREQUENCY OF HYPERCALCIURIA IN 4 TO 15 YEAR OLD CHILDREN". Çağdaş Tıp Dergisi 5 / 4 (February 2016): 226-233.