Yıl 2017, Cilt 7, Sayı 4, Sayfalar 385 - 390 2017-12-13

N-acetyl cysteine: Is it an option for treatment of drug induced acute pancreatitis?
N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi?

Osman Bülent Zülfikar [1] , Halil Haldun Emiroğlu [2]

59 111

Abstract

Aim: Drugs are a relatively rare cause of acute pancreatitis. We aimed a retrospective evaluation of 6 patients with drug induced acute pancreatitis, who were recovered after N-acetyl cysteine treatment.

Materials and Methods: .  The information in the files of 6 patients with drug induced acute pancreatitis who were improved after NAC treatment  between 2007 and 2017 was retrospectively reviewed. The criteria recommended by the International Study Group of Pediatric Pancreatitis were used for the diagnosis of acute pancreatitis in 6 patients. The severity of the disease was determined according to NASPGHAN criteria

Results: All of the 6 patients with drug induced acute pancreatitis who underwent NAC during the treatment of acute pancreatitis were completely healed.

Conclusion: NAC treatment seems to be beneficial for drug induced acute pancreatitis.

Amaç: Akut pankreatit etiyolojisinde ilaçlar nispeten seyrek bir nedendir. Çalışmamızda ilaç kullanımına bağlı akut pankreatit gelişen ve N-asetilsistein tedavisi sonrası iyileşen 6 hastanın retrospektif değerlendirmesini amaçlanmıştır.

Gereç ve Yöntem: 2007-2017 yılları arasında ilaca bağlı akut pankreatit tanısı alan ve NAC tedavisi uygulanan 6 çocuk hastanın dosyaları retrospektif olarak incelendi. Altı hastanın akut pankreatit tanısı "Uluslararası Çocuk Pankreatit Çalışma Grubu" tarafından önerilen kriterlere göre konuldu. Hastalığın şiddet derecesi NASPGHAN kriterlerine göre belirlendi.  

Bulgular: Akut pankreatit tedavisi sırasında NAC uygulanan ilaca bağlı akut pankreatitli 6 hastanın tümü tamamen iyileşti.

Sonuç: NAC, ilaca bağlı akut pankreatit tedavisi için faydalı görünmektedir.

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Konular Sağlık Bilimleri
Dergi Bölümü Orjinal Çalışma
Yazarlar

Yazar: Osman Bülent Zülfikar
E-posta: haldunemiroglu@gmail.com
Kurum: İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi ve Onkoloji Enstitüsü Çocuk Hematoloji-Onkoloji Bilim Dalı
Ülke: Turkey


Yazar: Halil Haldun Emiroğlu (Sorumlu Yazar)
E-posta: haldunemiroglu@gmail.com
Kurum: Selçuk Üniversitesi Tıp Fakültesi Çocuk Gastroenteroloji Bilim Dalı
Ülke: Turkey


Bibtex @araştırma makalesi { gopctd358803, journal = {Journal of Contemporary Medicine}, issn = {}, address = {Selçuk Üniversitesi}, year = {2017}, volume = {7}, pages = {385 - 390}, doi = {10.16899/gopctd.358803}, title = {N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi?}, key = {cite}, author = {Zülfikar, Osman Bülent and Emiroğlu, Halil Haldun} }
APA Zülfikar, O , Emiroğlu, H . (2017). N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi?. Journal of Contemporary Medicine, 7 (4), 385-390. DOI: 10.16899/gopctd.358803
MLA Zülfikar, O , Emiroğlu, H . "N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi?". Journal of Contemporary Medicine 7 (2017): 385-390 <http://dergipark.gov.tr/gopctd/issue/31866/358803>
Chicago Zülfikar, O , Emiroğlu, H . "N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi?". Journal of Contemporary Medicine 7 (2017): 385-390
RIS TY - JOUR T1 - N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi? AU - Osman Bülent Zülfikar , Halil Haldun Emiroğlu Y1 - 2017 PY - 2017 N1 - doi: 10.16899/gopctd.358803 DO - 10.16899/gopctd.358803 T2 - Journal of Contemporary Medicine JF - Journal JO - JOR SP - 385 EP - 390 VL - 7 IS - 4 SN - -2146-6009 M3 - doi: 10.16899/gopctd.358803 UR - http://dx.doi.org/10.16899/gopctd.358803 Y2 - 2017 ER -
EndNote %0 Journal of Contemporary Medicine N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi? %A Osman Bülent Zülfikar , Halil Haldun Emiroğlu %T N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi? %D 2017 %J Journal of Contemporary Medicine %P -2146-6009 %V 7 %N 4 %R doi: 10.16899/gopctd.358803 %U 10.16899/gopctd.358803