Yıl 2014, Cilt 4, Sayı 1, Sayfalar 41 - 43 2014-07-27

Severe pulmonary hypertension due to sleep-disordered breathing in an achondroplasic child
Akondroplazik Bir Çocukta Uykuda Solunum Bozukluğuna Bağlı Gelişen Ciddi Pulmoner Hipertansiyon

Vehbi Doğan [1] , Sema Taşkın [2] , Erhan Karaaslan [3] , Resul Yilmaz [4] , Nurşen Çakan [5]

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Achondroplasia is the most common skeletal dysplasia in children. Achondroplasic patients often have respiratory problems associated with upper respiratory tract obstruction and craniofacial dysmorphology. Chronic hypoxemia in these patients can result in pulmonary hypertension. In this report an achondroplasic child with severe day-time pulmonary hypertension is presented.

 

 

Akondroplazi çocuklarda en sık görülen iskelet displazisidir. Akondroplazik hastalarda üst solunum yollarının obstrüksiyonu ve kraniyofasiyal dismorfoloji nedeniyle solunum yolu yakınmaları sık görülmektedir. Bu hastalarda özellikle geceleri gelişen kronik hipoksemi pulmoner hipertansiyona yol açabilmektedir. Bu makalede ciddi gün içinde de devam eden pulmoner hipertansiyon gelişen akondroplazik bir çocuk sunulmuştur.
  • Horton WA, Hall JG, Hecht JT. Achondroplasia. Lancet 2007; 370:162–172
  • Zucconi M, Weber G, Castronovo V, Ferini-Strambi L, Russo F, Chiumello G, Smirne S. Sleep and upper airway obstruction in children with achondroplasia. J Pediatr. 1996;129(5):743-9
  • Mogayzel PJ Jr, Carroll JL, Loughlin GM, Hurko O, Francomano CA, Marcus CL. Sleep-disordered breathing in children with achondroplasia. J Pediatr. 1998;132:667-71.
  • Schlüter B, De Sousa G, Trowitzsch E, Andler W. Diagnostics and management of sleep-related respiratory disturbances in children with skeletal dysplasia caused by FGFR3 mutations (achondroplasia and hypochondroplasia). Georgian Med News. 2011;196-197:63-72
  • Apprill M, Weitzenblum E, Krieger J, Oswald M, Kurtz D. Frequency and mechanism of daytime pulmonary hypertension in patients with obstructive sleep apnea syndrome. Cor Vasa. 1991;33:42-9
  • Alchanatis M, Tourkohoriti G, Kakouros S, Kosmas E, Podaras S, Jordanoglou JB. Daytime pulmonary hypertension in patients with obstructive sleep apnea: the effect of continuous positive airway pressure in pulmonary hemodynamics. Respiration 2001;68:566-72.
  • Sajkov D, McEvoy RD. Obstructive sleep apnea and pulmonary hypertension. Prog Cardiovasc Dis. 2009;51:363-70
  • Adegunsoye A, Ramachandran S. Etiopathogenetic mechanisms of pulmonary hypertension in sleep-related breathing disorders. Pulm Med. 2012;2012:273591. doi: 10.1155/2012/273591. Epub 2012 Jul 11.
  • Ito T, Sawaishi Y, Ito Y, Sugawara A. Severe pulmonary hypertension in an infant with achondroplasia. Lancet 2001; 358:1062
  • Yıldırım SV, Durmaz C, Pourbagher MA, Erkan AN. A case of achondroplasia with severe pulmonary hypertension due to obstructive sleep apnea. Eur Arch Otorhinolaryngol. 2006;263:775-7
  • Sisk EA, Heatley DG, Borowski BJ, Leverson GE, Pauli RM. Obstructive sleep apnea in children with achondroplasia: surgical and anesthetic considerations. Otolaryngol Head Neck Surg. 1999;120:248-54
Birincil Dil en
Konular
Dergi Bölümü Olgu Sunumu
Yazarlar

Yazar: Vehbi Doğan

Yazar: Sema Taşkın

Yazar: Erhan Karaaslan

Yazar: Resul Yilmaz

Yazar: Nurşen Çakan

Bibtex @ { gopctd95652, journal = {Journal of Contemporary Medicine}, issn = {}, eissn = {2146-6009}, address = {Selçuk Üniversitesi}, year = {2014}, volume = {4}, pages = {41 - 43}, doi = {}, title = {Severe pulmonary hypertension due to sleep-disordered breathing in an achondroplasic child}, key = {cite}, author = {Doğan, Vehbi and Taşkın, Sema and Yilmaz, Resul and Çakan, Nurşen and Karaaslan, Erhan} }
APA Doğan, V , Taşkın, S , Karaaslan, E , Yilmaz, R , Çakan, N . (2014). Severe pulmonary hypertension due to sleep-disordered breathing in an achondroplasic child. Journal of Contemporary Medicine, 4 (1), 41-43. Retrieved from http://dergipark.gov.tr/gopctd/issue/7310/95652
MLA Doğan, V , Taşkın, S , Karaaslan, E , Yilmaz, R , Çakan, N . "Severe pulmonary hypertension due to sleep-disordered breathing in an achondroplasic child". Journal of Contemporary Medicine 4 (2014): 41-43 <http://dergipark.gov.tr/gopctd/issue/7310/95652>
Chicago Doğan, V , Taşkın, S , Karaaslan, E , Yilmaz, R , Çakan, N . "Severe pulmonary hypertension due to sleep-disordered breathing in an achondroplasic child". Journal of Contemporary Medicine 4 (2014): 41-43
RIS TY - JOUR T1 - Severe pulmonary hypertension due to sleep-disordered breathing in an achondroplasic child AU - Vehbi Doğan , Sema Taşkın , Erhan Karaaslan , Resul Yilmaz , Nurşen Çakan Y1 - 2014 PY - 2014 N1 - DO - T2 - Journal of Contemporary Medicine JF - Journal JO - JOR SP - 41 EP - 43 VL - 4 IS - 1 SN - -2146-6009 M3 - UR - Y2 - 2019 ER -
EndNote %0 Journal of Contemporary Medicine Severe pulmonary hypertension due to sleep-disordered breathing in an achondroplasic child %A Vehbi Doğan , Sema Taşkın , Erhan Karaaslan , Resul Yilmaz , Nurşen Çakan %T Severe pulmonary hypertension due to sleep-disordered breathing in an achondroplasic child %D 2014 %J Journal of Contemporary Medicine %P -2146-6009 %V 4 %N 1 %R %U
ISNAD Doğan, Vehbi , Taşkın, Sema , Karaaslan, Erhan , Yilmaz, Resul , Çakan, Nurşen . "Akondroplazik Bir Çocukta Uykuda Solunum Bozukluğuna Bağlı Gelişen Ciddi Pulmoner Hipertansiyon". Journal of Contemporary Medicine 4 / 1 (Temmuz 2014): 41-43.