Yıl 2018, Cilt 5, Sayı 2, Sayfalar 149 - 155 2018-04-14

Transgenerational Transmission of Radiation-Induced Expression Patterns of Arabidopsis Thaliana (L.) Heynh. Rad51 and Rad1 Genes

Sergey Litvinov [1] , Namik Rashydov [2]

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Transcription rates of the genes AtKu70, AtRAD51, AtRad1, involved in maintaining Arabidopsis thaliana genome stability, in relation to the modification of phenotypic characteristics in irradiated plants and their progeny after the action of acute and fractionated X-ray radiation were studied. Differences in the transcription rate were measured by densitometric analysis of cDNA, synthesized by reverse transcription at the template of mRNAs, extracted from fresh leaves after 2 hours irradiation treatment. The doses 3 Gy, 12 Gy, 15 Gy and 21 Gy with 1.48 Gy/s specific dose rate were applied. Significant correlation between phenotype modifications in F0 and F1 generations, between phenotype traits and caretaker genes activity in irradiated F0 plants were shown. Also preservation of changes in the pattern of AtRad1 and AtRAD51 but not AtKu70 expression in F1 plant leaves had been revealed. Changes in F1 compared with F0 generation do not correspond to the extrapolation of dependence between the phenotypic modifications and DNA repair genes transcription rate in the leaves of irradiated plants. Based on the obtained data it could be suggested that the altered transcriptional activity of AtRAD51 and AtRad1 reflects the transfer of DNA lesions from parent to offspring.

Genes expression, X-ray irradiation, DNA repair, Transgenerational inheritance
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Birincil Dil en
Konular Biyoloji
Yayımlanma Tarihi July
Dergi Bölümü Makaleler
Yazarlar

Orcid: orcid.org/0000-0002-9185-4807
Yazar: Sergey Litvinov (Sorumlu Yazar)
E-posta: slitvinov83@gmail.com
Kurum: Institute Cell Biology & Genetic Engineering of NAS of Ukraine
Ülke: Ukraine


Orcid: orcid.org/0000-0001-5387-4877
Yazar: Namik Rashydov
E-posta: nrashydov@yahoo.com
Kurum: Institute Cell Biology & Genetic Engineering of NAS of Ukraine
Ülke: Ukraine


Bibtex @araştırma makalesi { ijsm415191, journal = {International Journal of Secondary Metabolite}, issn = {}, address = {İzzet KARA}, year = {2018}, volume = {5}, pages = {149 - 155}, doi = {10.21448/ijsm.415191}, title = {Transgenerational Transmission of Radiation-Induced Expression Patterns of Arabidopsis Thaliana (L.) Heynh. Rad51 and Rad1 Genes}, key = {cite}, author = {Litvinov, Sergey and Rashydov, Namik} }
APA Litvinov, S , Rashydov, N . (2018). Transgenerational Transmission of Radiation-Induced Expression Patterns of Arabidopsis Thaliana (L.) Heynh. Rad51 and Rad1 Genes. International Journal of Secondary Metabolite, 5 (2), 149-155. DOI: 10.21448/ijsm.415191
MLA Litvinov, S , Rashydov, N . "Transgenerational Transmission of Radiation-Induced Expression Patterns of Arabidopsis Thaliana (L.) Heynh. Rad51 and Rad1 Genes". International Journal of Secondary Metabolite 5 (2018): 149-155 <http://dergipark.gov.tr/ijsm/issue/34119/415191>
Chicago Litvinov, S , Rashydov, N . "Transgenerational Transmission of Radiation-Induced Expression Patterns of Arabidopsis Thaliana (L.) Heynh. Rad51 and Rad1 Genes". International Journal of Secondary Metabolite 5 (2018): 149-155
RIS TY - JOUR T1 - Transgenerational Transmission of Radiation-Induced Expression Patterns of Arabidopsis Thaliana (L.) Heynh. Rad51 and Rad1 Genes AU - Sergey Litvinov , Namik Rashydov Y1 - 2018 PY - 2018 N1 - doi: 10.21448/ijsm.415191 DO - 10.21448/ijsm.415191 T2 - International Journal of Secondary Metabolite JF - Journal JO - JOR SP - 149 EP - 155 VL - 5 IS - 2 SN - -2148-6905 M3 - doi: 10.21448/ijsm.415191 UR - http://dx.doi.org/10.21448/ijsm.415191 Y2 - 2018 ER -
EndNote %0 International Journal of Secondary Metabolite Transgenerational Transmission of Radiation-Induced Expression Patterns of Arabidopsis Thaliana (L.) Heynh. Rad51 and Rad1 Genes %A Sergey Litvinov , Namik Rashydov %T Transgenerational Transmission of Radiation-Induced Expression Patterns of Arabidopsis Thaliana (L.) Heynh. Rad51 and Rad1 Genes %D 2018 %J International Journal of Secondary Metabolite %P -2148-6905 %V 5 %N 2 %R doi: 10.21448/ijsm.415191 %U 10.21448/ijsm.415191