Yıl 2018, Cilt 5, Sayı 3, Sayfalar 259 - 269 2018-09-15

Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia

Ebru Deveci [1] , Gülsen Tel-Çayan [2] , Mehmet Emin Duru [3]

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In this study, chemical composition, antioxidant, anticholinesterase and anti-urease activities of the essential oil, hexane, acetone, methanol and water extracts of Euphorbia helioscopia were investigated. The chemical composition of the essential oil was analyzed by GC and GC/MS and β-cubebene (19.3 %), palmitic acid (12.2 %) and caryophyllene oxide (11.7 %) were identified as major compounds. The antioxidant activity of essential oil and extracts was performed by several methods such as β-carotene-linoleic acid, DPPH, ABTS•+ radical scavenging, CUPRAC and metal chelating assays. The water extract showed higher antioxidant activity than BHA and α-tocopherol in β-carotene-linoleic acid, DPPH, ABTS•+ and CUPRAC assays with IC50: 1.08±0.39, 15.57±0.48, 1.89±0.33 and 12.50±0.11 μg/mL values, respectively. Also, the anticholinesterase and anti-urease activities were tested against acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and urease enzymes, spectrophotometrically. The acetone extract (81.23±0.58 %) showed very close BChE inhibitory activity to galantamine. The hexane extract (96.97±0.36 %) of E. helioscopia showed higher anti-urease activity than thiourea (96.93±0.17 %) whereas the essential oil (91.37±0.26 %) indicated very close anti-urease activity to the standard.

Euphorbia helioscopia, Essential oil, Antioxidant activity, Anticholinesterase activity, Anti-urease activity
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Birincil Dil en
Konular Biyoloji
Yayımlanma Tarihi September
Dergi Bölümü Makaleler
Yazarlar

Yazar: Ebru Deveci
Kurum: Muğla Sıtkı Koçman University, Faculty of Sciences, Department of Chemistry
Ülke: Turkey


Orcid: 0000-0002-1916-7391
Yazar: Gülsen Tel-Çayan (Sorumlu Yazar)
Kurum: Muğla Sıtkı Koçman University, Muğla Vocational School, Department of Chemistry and Chemical Processing Technologies
Ülke: Turkey


Yazar: Mehmet Emin Duru
Kurum: Muğla Sıtkı Koçman University, Faculty of Sciences, Department of Chemistry
Ülke: Turkey


Bibtex @araştırma makalesi { ijsm433681, journal = {International Journal of Secondary Metabolite}, issn = {}, eissn = {2148-6905}, address = {İzzet KARA}, year = {2018}, volume = {5}, pages = {259 - 269}, doi = {10.21448/ijsm.433681}, title = {Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia}, key = {cite}, author = {Duru, Mehmet Emin and Tel-Çayan, Gülsen and Deveci, Ebru} }
APA Deveci, E , Tel-Çayan, G , Duru, M . (2018). Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia. International Journal of Secondary Metabolite, 5 (3), 259-269. DOI: 10.21448/ijsm.433681
MLA Deveci, E , Tel-Çayan, G , Duru, M . "Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia". International Journal of Secondary Metabolite 5 (2018): 259-269 <http://dergipark.gov.tr/ijsm/issue/37294/433681>
Chicago Deveci, E , Tel-Çayan, G , Duru, M . "Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia". International Journal of Secondary Metabolite 5 (2018): 259-269
RIS TY - JOUR T1 - Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia AU - Ebru Deveci , Gülsen Tel-Çayan , Mehmet Emin Duru Y1 - 2018 PY - 2018 N1 - doi: 10.21448/ijsm.433681 DO - 10.21448/ijsm.433681 T2 - International Journal of Secondary Metabolite JF - Journal JO - JOR SP - 259 EP - 269 VL - 5 IS - 3 SN - -2148-6905 M3 - doi: 10.21448/ijsm.433681 UR - http://dx.doi.org/10.21448/ijsm.433681 Y2 - 2018 ER -
EndNote %0 International Journal of Secondary Metabolite Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia %A Ebru Deveci , Gülsen Tel-Çayan , Mehmet Emin Duru %T Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia %D 2018 %J International Journal of Secondary Metabolite %P -2148-6905 %V 5 %N 3 %R doi: 10.21448/ijsm.433681 %U 10.21448/ijsm.433681
ISNAD Deveci, Ebru , Tel-Çayan, Gülsen , Duru, Mehmet Emin . "Investigation of Chemical Composition, Antioxidant, Anticholinesterase and Anti-urease activities of Euphorbia helioscopia". International Journal of Secondary Metabolite 5 / 3 (Eylül 2018): 259-269. http://dx.doi.org/10.21448/ijsm.433681