Yıl 2014, Cilt , Sayı 2, Sayfalar 16 - 21 2014-07-01

Screening of Antimicrobial and Anticancer Potentials of Some Plant Extracts from Mugla Provience

Hatice GÜNEŞ [1] , Müjgan OKTAY [2] , Fulya ÇELEBİ [3] , Bahar TÜL [4]

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Many phytochemicals from different plant species have potency in treatment and prevention of cancer. Currently, substantial research have being carried out in many laboratories the world over to discover new plant extracts with high anticancer and/or antimicrobial activities. In this study, seven different plant species Glaucium flavum, Euphorbia falcata, Conyza canadensis, Chenopodium botrys, Catalpa sp., Quercus coccifera, Crataegus monogyna from Mugla region were examined for their antimicrobial and anticancer capacities. Disc diffusion method was used to study antimicrobial potency of ethanol extracts against Gram-positive and Gram-negative bacteria. Anticancer activities of the plant extracts were tested against the six different cancer cell lines using the MTT assay. The fruit extract of Q. coccifera was found to be the most effective extract (13-15 mm 80µg/disc inhibition zone) against S. albus, M. luteus and S.aureus. In addition, C. canadensis exhibited antimicrobial activity only against E.coli and B. subtilis (10-14 mm 80µg/ml inhibition zone). Based on MTT assays, all of the plant extracts resulted in different degrees of anticancer activity on six different cancer cell lines. The most effective extracts were from C. botrys, G. flavum, Catalpa sp and Q. coccifera which caused more than threefold decrease in the cell proliferation of K562, PC-3 and MCF-7 cell lines compared to control. In conclusion, among the seven tested plant extracts, only Q. coccifera and C. canadensis showed antimicrobial capacity. On the other hand, 4 plant extracts have displayed high anticancer potency. Future studies related with cell death will elicit the mechanisms of anti-tumor activities of the plant extracts
Plant extracts, Anti-microbial activity, Anti-cancer activity, Cancer cell lines
Konular
Diğer ID JA38GP47MM
Dergi Bölümü Araştırma Makalesi
Yazarlar

Yazar: Hatice GÜNEŞ

Yazar: Müjgan OKTAY

Yazar: Fulya ÇELEBİ

Yazar: Bahar TÜL

Bibtex @ { jabs387537, journal = {Journal of Applied Biological Sciences}, issn = {}, eissn = {2146-0108}, address = {Nobel Bilim ve Araştırma Merkezi Limited}, year = {2014}, volume = {}, pages = {16 - 21}, doi = {}, title = {Screening of Antimicrobial and Anticancer Potentials of Some Plant Extracts from Mugla Provience}, key = {cite}, author = {OKTAY, Müjgan and GÜNEŞ, Hatice and ÇELEBİ, Fulya and TÜL, Bahar} }
APA GÜNEŞ, H , OKTAY, M , ÇELEBİ, F , TÜL, B . (2014). Screening of Antimicrobial and Anticancer Potentials of Some Plant Extracts from Mugla Provience. Journal of Applied Biological Sciences, (2), 16-21. Retrieved from http://dergipark.gov.tr/jabs/issue/34935/387537
MLA GÜNEŞ, H , OKTAY, M , ÇELEBİ, F , TÜL, B . "Screening of Antimicrobial and Anticancer Potentials of Some Plant Extracts from Mugla Provience". Journal of Applied Biological Sciences (2014): 16-21 <http://dergipark.gov.tr/jabs/issue/34935/387537>
Chicago GÜNEŞ, H , OKTAY, M , ÇELEBİ, F , TÜL, B . "Screening of Antimicrobial and Anticancer Potentials of Some Plant Extracts from Mugla Provience". Journal of Applied Biological Sciences (2014): 16-21
RIS TY - JOUR T1 - Screening of Antimicrobial and Anticancer Potentials of Some Plant Extracts from Mugla Provience AU - Hatice GÜNEŞ , Müjgan OKTAY , Fulya ÇELEBİ , Bahar TÜL Y1 - 2014 PY - 2014 N1 - DO - T2 - Journal of Applied Biological Sciences JF - Journal JO - JOR SP - 16 EP - 21 VL - IS - 2 SN - -2146-0108 M3 - UR - Y2 - 2019 ER -
EndNote %0 Journal of Applied Biological Sciences Screening of Antimicrobial and Anticancer Potentials of Some Plant Extracts from Mugla Provience %A Hatice GÜNEŞ , Müjgan OKTAY , Fulya ÇELEBİ , Bahar TÜL %T Screening of Antimicrobial and Anticancer Potentials of Some Plant Extracts from Mugla Provience %D 2014 %J Journal of Applied Biological Sciences %P -2146-0108 %V %N 2 %R %U
ISNAD GÜNEŞ, Hatice , OKTAY, Müjgan , ÇELEBİ, Fulya , TÜL, Bahar . "Screening of Antimicrobial and Anticancer Potentials of Some Plant Extracts from Mugla Provience". Journal of Applied Biological Sciences / 2 (Temmuz 2014): 16-21.