Yıl 2018, Cilt 3, Sayı 2, Sayfalar 52 - 58 2018-08-17

Pseudohypoparathyroidism and Seizure: A Rare Case Report

FERHAT GÖKAY [1] , YASİN ŞİMŞEK [2] , OĞUZHAN SITKI DİZDAR [3]

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Pseudohypoparathyroidism is characterized by hypocalcemia, hyperphosphatemia, increased serum parathyroid hormone values and insensitivity to the biological activity of parathyroid hormone. Pseudohypoparathyroidism is often associated with a characteristic phenotype known as Albright‘s hereditary osteodystrophy. Pseudohypoparathyroidism usually presents at an early age. We describe a 50-year-old man who presented with seizure due to hypocalcemia. He has typical features of Albright's hereditary osteodystrophy, which include a round face, short neck and stature.  Diffuse calsifications were seen on the bilateral cerebellum, putamen and dentate nucleus in computerized tomography. The patient is treated successfully by calcium carbonate and calcitriol supplementation This case was reported in order to remind pseudohypoparathyroidism in patients with hypocalcemic seizures.

Pseudohypoparathyroidism, seizure, calcification
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  • Melmed S, Polonsky KS, Larsen PR, Kronenberg HM. Williams Textbook of Endocrinology. In: Bringhurst FR, Demay MB, Kronenberg HM. Hormones and disorders of mineral metabolism. Saunders, Philadelphia, 2011;1280-1283.
  • Liu J, Erlichman B, Weinstein LS. The stimulatory G protein alpha-subunit Gs alpha is imprinted in human thyroid glands: implications for thyroid function in pseudohypoparathyroidism types 1A and 1B. J Clin Endocrinol Metab 2003;88:4336–4341
  • Mantovani G. Pseudohypoparathyroidism: diagnosis and treatment. The Journal of Clinical Endocrinology & Metabolism 2011;96:3020-3030.
  • Donghi V, Mora S, Zamproni I, Chiumello G, Weber G. Pseudohypoparathyroidism, an often delayed diagnosis: a case series. Cases J 2009;2:6734.
  • Seki T, Yamamoto M, Kimura H, Tsuiki M, Ono M, Miki N, Takano K, Sato K: Vitamin D deficiency in two young adults with biochemical findings resembling pseudohypoparathyroidism type I and type II. Endocr J 2010; 57:735-744.
Konular
Dergi Bölümü Makaleler
Yazarlar

Yazar: FERHAT GÖKAY
Kurum: Kayseri Eğitim Araştırma Hastanesi
Ülke: Turkey


Yazar: YASİN ŞİMŞEK
Kurum: Kayseri Eğitim Araştırma Hastanesi
Ülke: Turkey


Yazar: OĞUZHAN SITKI DİZDAR
Kurum: Kayseri Eğitim Araştırma Hastanesi
Ülke: Turkey


Bibtex @olgu sunumu { jamer285109, journal = {Journal of Anatolian Medical Research}, issn = {}, eissn = {2587-1153}, address = {Kayseri EAH}, year = {2018}, volume = {3}, pages = {52 - 58}, doi = {}, title = {Pseudohypoparathyroidism and Seizure: A Rare Case Report}, key = {cite}, author = {ŞİMŞEK, YASİN and DİZDAR, OĞUZHAN SITKI and GÖKAY, FERHAT} }
APA GÖKAY, F , ŞİMŞEK, Y , DİZDAR, O . (2018). Pseudohypoparathyroidism and Seizure: A Rare Case Report. Journal of Anatolian Medical Research, 3 (2), 52-58. Retrieved from http://dergipark.gov.tr/jamer/issue/38895/285109
MLA GÖKAY, F , ŞİMŞEK, Y , DİZDAR, O . "Pseudohypoparathyroidism and Seizure: A Rare Case Report". Journal of Anatolian Medical Research 3 (2018): 52-58 <http://dergipark.gov.tr/jamer/issue/38895/285109>
Chicago GÖKAY, F , ŞİMŞEK, Y , DİZDAR, O . "Pseudohypoparathyroidism and Seizure: A Rare Case Report". Journal of Anatolian Medical Research 3 (2018): 52-58
RIS TY - JOUR T1 - Pseudohypoparathyroidism and Seizure: A Rare Case Report AU - FERHAT GÖKAY , YASİN ŞİMŞEK , OĞUZHAN SITKI DİZDAR Y1 - 2018 PY - 2018 N1 - DO - T2 - Journal of Anatolian Medical Research JF - Journal JO - JOR SP - 52 EP - 58 VL - 3 IS - 2 SN - -2587-1153 M3 - UR - Y2 - 2018 ER -
EndNote %0 Journal of Anatolian Medical Research Pseudohypoparathyroidism and Seizure: A Rare Case Report %A FERHAT GÖKAY , YASİN ŞİMŞEK , OĞUZHAN SITKI DİZDAR %T Pseudohypoparathyroidism and Seizure: A Rare Case Report %D 2018 %J Journal of Anatolian Medical Research %P -2587-1153 %V 3 %N 2 %R %U
ISNAD GÖKAY, FERHAT , ŞİMŞEK, YASİN , DİZDAR, OĞUZHAN SITKI . "Pseudohypoparathyroidism and Seizure: A Rare Case Report". Journal of Anatolian Medical Research 3 / 2 (Ağustos 2018): 52-58.