Year 2018, Volume 1, Issue 3, Pages 33 - 33 2018-12-08

Fatty Acid Analysis and Biological Activity of Jordanian Propolis

Ashok K. SHAKYA [1] , Shankar KATEKHAYE [2] , Ghaleb A. ORIQUAT [3] , Rajashri R. NAIK [4] , Rajashri R. NAIK [5] , Anant PARADKAR [6] , Hugo FEARNLEY [7] , James FEARNLEY [8]

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Propolis is a resinous natural product collected by bees (Apis mellifera) from tree exudates which is widely used in folk medicine1. Reports on Jordanian Propolis reveal the presence of new chemical compound 4(Z)-1-3-dihydroxyeupha-7,24-dien-26-oic acid2 along with other compounds like pinobanksin-3-O-acetate, pinocemberin, chrysin3 and lignoceric acid2. The present study was carried out to investigate the fatty acid composition, antioxidant and xanthine oxidase inhibition activity of Jordanian Propolis, collected from Al-Ghour region. The hexane extract of Jordanian Propolis contains different fatty acids, which are reported first time, using GC-FID. The major fatty acid identified were palmitic acid (44.5%), Oleic acid (18:19cis, 24.6%), Arachidic acid (7.4%), Stearic acid (5.4%), linoleic acid (18:29-12cis, 3.1%), caprylic acid (2.9%),  lignoceric acid (2.6%), cis-11,14-eicosadienoic acid (20:211-14cis, 2.4%), palmitoleic acid (1.5%), cis-11-eicosenoic acid (1.2%), α–linolenic acid (18:39-12-15cis, 1.1%), cis-13,16-docosadienoic acid (22:213-16cis, 1.0%), along with minor constituents like saturated fatty acids. Antioxidant properties of the hexane extract were determined via DPPH radical scavenging, β-carotene bleaching assay and NO scavenging assay. The extract produced significant antioxidant activity in-vitro. The extract also exhibit appreciable xanthine oxidase inhibitory activity in-vitro.
Propolis, Naturel product, DPPH, In vitro
  • 1. Toreti, V.C., Sato, H.H., Pastore, G.M. and Park, Y.K., 2013. Recent progress of propolis for its biological and chemical compositions and its botanical origin. Evidence-based complementary and alternative medicine, 2013. http://dx.doi.org/10.1155/2013/697390
  • 2. Shaheen, S.A., Zarga, M.H.A., Nazer, I.K., Darwish, R.M. and Al-Jaber, H.I., 2011. Chemical constituents of Jordanian propolis. Natural product research, 25(14), 1312-1318.
  • 3. Darwish, R.M., Ra'ed, J., Zarga, M.H.A. and Nazer, I.K., 2010. Antibacterial effect of Jordanian propolis and isolated flavonoids against human pathogenic bacteria. African Journal of Biotechnology, 9(36). 5966-5974
Primary Language en
Subjects
Journal Section 2nd Propolis Conference Special Issue
Authors

Author: Ashok K. SHAKYA

Author: Shankar KATEKHAYE

Author: Ghaleb A. ORIQUAT

Author: Rajashri R. NAIK

Author: Rajashri R. NAIK

Author: Anant PARADKAR

Author: Hugo FEARNLEY

Author: James FEARNLEY

Bibtex @conference paper { jan489238, journal = {Journal of Apitherapy and Nature}, issn = {}, eissn = {2667-4734}, address = {Oktay YILDIZ}, year = {2018}, volume = {1}, pages = {33 - 33}, doi = {}, title = {Fatty Acid Analysis and Biological Activity of Jordanian Propolis}, key = {cite}, author = {SHAKYA, Ashok K. and KATEKHAYE, Shankar and ORIQUAT, Ghaleb A. and NAIK, Rajashri R. and NAIK, Rajashri R. and PARADKAR, Anant and FEARNLEY, Hugo and FEARNLEY, James} }
APA SHAKYA, A , KATEKHAYE, S , ORIQUAT, G , NAIK, R , NAIK, R , PARADKAR, A , FEARNLEY, H , FEARNLEY, J . (2018). Fatty Acid Analysis and Biological Activity of Jordanian Propolis. Journal of Apitherapy and Nature, 1 (3), 33-33. Retrieved from http://dergipark.gov.tr/jan/issue/40577/489238
MLA SHAKYA, A , KATEKHAYE, S , ORIQUAT, G , NAIK, R , NAIK, R , PARADKAR, A , FEARNLEY, H , FEARNLEY, J . "Fatty Acid Analysis and Biological Activity of Jordanian Propolis". Journal of Apitherapy and Nature 1 (2018): 33-33 <http://dergipark.gov.tr/jan/issue/40577/489238>
Chicago SHAKYA, A , KATEKHAYE, S , ORIQUAT, G , NAIK, R , NAIK, R , PARADKAR, A , FEARNLEY, H , FEARNLEY, J . "Fatty Acid Analysis and Biological Activity of Jordanian Propolis". Journal of Apitherapy and Nature 1 (2018): 33-33
RIS TY - JOUR T1 - Fatty Acid Analysis and Biological Activity of Jordanian Propolis AU - Ashok K. SHAKYA , Shankar KATEKHAYE , Ghaleb A. ORIQUAT , Rajashri R. NAIK , Rajashri R. NAIK , Anant PARADKAR , Hugo FEARNLEY , James FEARNLEY Y1 - 2018 PY - 2018 N1 - DO - T2 - Journal of Apitherapy and Nature JF - Journal JO - JOR SP - 33 EP - 33 VL - 1 IS - 3 SN - -2667-4734 M3 - UR - Y2 - 2019 ER -
EndNote %0 Journal of Apitherapy and Nature Fatty Acid Analysis and Biological Activity of Jordanian Propolis %A Ashok K. SHAKYA , Shankar KATEKHAYE , Ghaleb A. ORIQUAT , Rajashri R. NAIK , Rajashri R. NAIK , Anant PARADKAR , Hugo FEARNLEY , James FEARNLEY %T Fatty Acid Analysis and Biological Activity of Jordanian Propolis %D 2018 %J Journal of Apitherapy and Nature %P -2667-4734 %V 1 %N 3 %R %U
ISNAD SHAKYA, Ashok K. , KATEKHAYE, Shankar , ORIQUAT, Ghaleb A. , NAIK, Rajashri R. , NAIK, Rajashri R. , PARADKAR, Anant , FEARNLEY, Hugo , FEARNLEY, James . "Fatty Acid Analysis and Biological Activity of Jordanian Propolis". Journal of Apitherapy and Nature 1 / 3 (December 2018): 33-33.