Yıl 2018, Cilt 11, Sayı 1, Sayfalar 18 - 23 2018-03-01

Işık Miksrokobik Bir Çalışma: Devede Konjunktiva ile İlişkili Lenfoid Doku
A Light Microscopic Study: Conjunctiva-Associated Lymphoid Tissue in Camel

Ahmet CEYLAN [1]

52 110

Konjunktiva ile ilişkili lenfoid doku (CALT), gözün en önemli aksesuar bileşenlerinden biridir. Bu çalışma, sağlıklı develerde konjunktiva ile ilişkili lenfoid dokunun histolojik dağılımını ve karakteristik özelliklerini ışık mikroskobu tekniğiyle ortaya koymak amacıyla yapıldı. Çalışmada toplam 5 adet (13-19 yaş aralığında) deveye ait alt ve üst göz kapağı kullanıldı. CALT’a ait genel makroskobik görünüm asetik asit uygulamasıyla ortaya konuldu. Tüm develerde CALT’ın en önemli elemanları olan ve soliter ve agregat lenf foliküllerinin varlığı tespit edildi. Foliküllerin üzerlerinin folikülle ilişkili epitel (FAE) olarak bilinen ve intra epiteliyal lenfositleri barındıran, kadeh hücrelerinin görülmediği ince, yassılaşmış epitel ile örtülü olduğu görüldü. Buna ek olarak, lenf foliküllerinin germinal merkez, korona, dom bölgesi ve inter foliküler alanlardan meydana geldiği fark edildi. İnterfoliküler alanlarda CALT en önemli karakteristik özelliklerinden bir olan, yüksek endotelli venüllerin varlığı ortaya konuldu. Sonuç olarak, deve CALT’ının sahip olduğu belirleyici özellikleriyle diğer mukozal lenfoid dokularla oldukça yüksek benzelikler göterdiği ve oküler savunma mekanizması içerisinde önemli bir rol oynadığı kanısına varıldı.

Conjunctiva-associated lymphoid tissue (CALT) is one of the most important accessory component of the eye. This study was undertaken to demostrate the histological distribution and characteristic features of CALT in healhty camels using light microscopy technique. A total upper and lower eyelids of 5 (age range, 13-19) camels were investigated. The gross appearance of CALT were revealed by acetic acid application. Fully intact solitary and aggregated lymphoid follicles were observed as members of CALT in all camels. These follicles were covered by a thin, flattened epitehelium called follicular-associated epithelium (FAE) that contained intra epithelial lymphocytes and lacked goblet cells. In addition germinal centers, corona, subepithelial dome region and interfolliculer areas were noticed within the lymphoid follicles. The presence of high endothelial venules (HEV), a highly distinctive feature of CALT, was confirmed in interfollicular areas. We conclude that CALT of camel closely resembles other mucosal lymphoid tissues and may serve as an important member of ocular defense mechanism with its determinative features.

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Birincil Dil tr
Konular Yaşam Bilimleri
Dergi Bölümü ARAŞTIRMA MAKALESİ
Yazarlar

Yazar: Ahmet CEYLAN (Sorumlu Yazar)
E-posta: ceylan@ankara.edu.tr

Bibtex @araştırma makalesi { kvj374609, journal = {Kocatepe Veteriner Dergisi}, issn = {1308-1594}, address = {Afyon Kocatepe Üniversitesi}, year = {2018}, volume = {11}, pages = {18 - 23}, doi = {}, title = {Işık Miksrokobik Bir Çalışma: Devede Konjunktiva ile İlişkili Lenfoid Doku}, key = {cite}, author = {CEYLAN, Ahmet} }
APA CEYLAN, A . (2018). Işık Miksrokobik Bir Çalışma: Devede Konjunktiva ile İlişkili Lenfoid Doku. Kocatepe Veteriner Dergisi, 11 (1), 18-23. Retrieved from http://dergipark.gov.tr/kvj/issue/33193/374609
MLA CEYLAN, A . "Işık Miksrokobik Bir Çalışma: Devede Konjunktiva ile İlişkili Lenfoid Doku". Kocatepe Veteriner Dergisi 11 (2018): 18-23 <http://dergipark.gov.tr/kvj/issue/33193/374609>
Chicago CEYLAN, A . "Işık Miksrokobik Bir Çalışma: Devede Konjunktiva ile İlişkili Lenfoid Doku". Kocatepe Veteriner Dergisi 11 (2018): 18-23
RIS TY - JOUR T1 - Işık Miksrokobik Bir Çalışma: Devede Konjunktiva ile İlişkili Lenfoid Doku AU - Ahmet CEYLAN Y1 - 2018 PY - 2018 N1 - DO - T2 - Kocatepe Veteriner Dergisi JF - Journal JO - JOR SP - 18 EP - 23 VL - 11 IS - 1 SN - 1308-1594-2147-6853 M3 - UR - Y2 - 2017 ER -
EndNote %0 Kocatepe Veteriner Dergisi Işık Miksrokobik Bir Çalışma: Devede Konjunktiva ile İlişkili Lenfoid Doku %A Ahmet CEYLAN %T Işık Miksrokobik Bir Çalışma: Devede Konjunktiva ile İlişkili Lenfoid Doku %D 2018 %J Kocatepe Veteriner Dergisi %P 1308-1594-2147-6853 %V 11 %N 1 %R %U