Yıl 2018, Cilt 5, Sayı 4, Sayfalar 169 - 173 2018-04-30

Thoracoabdominal asynchrony correlates with peripheral vascular resistance changes in a cohort of obese children.

Marco Zaffanello [1] , Franco Antoniazzi [2] , Laura Tenero [3] , Michele Piazza [4] , Angelo Pietrobelli [5] , giuseppe Lippi [6] , Emma Gasperi [7] , giorgio Piacentini [8]

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Objective: The purpose of this study was to assess the relationship between the thoracoabdominal asynchrony (phase angle), as an index of inspiratory airflow resistance, pulse transit time arousal index (PTT Ar/I), as changes in peripheral vascular resistance and intrathoracic pressure, and obstructive apnea index (OA), Oxygen Desaturation Index (ODI), snoring (% estimated Total Sleep Time - eTST) and apnea-hypopnea index (AHI) in a cohort of exogenous obese children.

Material and Methods: Body mass index (BMI) and BMI z-scores were calculated according to age and sex in 36 consecutive obese children. Nasal patency, tonsil size, Friedman palate position scoring were also recorded. An overnight sleep respiratory recording was performed using an polygraphic ambulatory device.

Results:  Subjects studies had normal to mild sleep respiratory involvement (assessed by respiratory polysomnographic scoring). Phase angle correlated significantly with PTT Ar/I, but not with AHI (n/hr), OA (n/hr), ODI (n/hr) and snoring (% eTST), even adjusting for nasal patency, tonsil hypertrophy, palate position and BMI (z-score).

Conclusion: Thoracoabdominal asynchrony (phase angle) is correlated with peripheral vascular resistance changes (PTT Ar/I), suggesting a subclinical upper respiratory airflow anomaly with autonomic activation in obese subjects.


phase angle, pulse transit time, obesity, children, overnight respiratory polygraphy.
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Yazar: Marco Zaffanello (Sorumlu Yazar)
E-posta: marco.zaffanello@univr.it
Kurum: Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona
Ülke: Italy


Yazar: Franco Antoniazzi
E-posta: franco.antoniazzi@univr.it
Kurum: Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona
Ülke: Italy


Yazar: Laura Tenero
E-posta: laura.tenero@univr.it
Kurum: Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona
Ülke: Italy


Yazar: Michele Piazza
E-posta: michele.piazza@univr.it
Kurum: Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona
Ülke: Italy


Yazar: Angelo Pietrobelli
E-posta: angelo.pietrobelli@univr.it
Kurum: Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona
Ülke: Italy


Yazar: giuseppe Lippi
E-posta: giuseppe.lippi@univr.it
Kurum: Section of Clinical Biochemistry, University of Verona, Verona
Ülke: Italy


Yazar: Emma Gasperi
E-posta: emma.gasperi@univr.it
Kurum: Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona
Ülke: Italy


Yazar: giorgio Piacentini
E-posta: giorgio.piacentini@univr.it
Kurum: Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona
Ülke: Italy


Bibtex @araştırma makalesi { msd411431, journal = {Medical Science and Discovery}, issn = {2148-6832}, address = {Lycia Press Inc.}, year = {2018}, volume = {5}, pages = {169 - 173}, doi = {10.17546/msd.411431}, title = {Thoracoabdominal asynchrony correlates with peripheral vascular resistance changes in a cohort of obese children.}, key = {cite}, author = {Lippi, giuseppe and Piacentini, giorgio and Piazza, Michele and Zaffanello, Marco and Tenero, Laura and Antoniazzi, Franco and Gasperi, Emma and Pietrobelli, Angelo} }
APA Zaffanello, M , Antoniazzi, F , Tenero, L , Piazza, M , Pietrobelli, A , Lippi, g , Gasperi, E , Piacentini, g . (2018). Thoracoabdominal asynchrony correlates with peripheral vascular resistance changes in a cohort of obese children.. Medical Science and Discovery, 5 (4), 169-173. DOI: 10.17546/msd.411431
MLA Zaffanello, M , Antoniazzi, F , Tenero, L , Piazza, M , Pietrobelli, A , Lippi, g , Gasperi, E , Piacentini, g . "Thoracoabdominal asynchrony correlates with peripheral vascular resistance changes in a cohort of obese children.". Medical Science and Discovery 5 (2018): 169-173 <http://dergipark.gov.tr/msd/issue/35277/411431>
Chicago Zaffanello, M , Antoniazzi, F , Tenero, L , Piazza, M , Pietrobelli, A , Lippi, g , Gasperi, E , Piacentini, g . "Thoracoabdominal asynchrony correlates with peripheral vascular resistance changes in a cohort of obese children.". Medical Science and Discovery 5 (2018): 169-173
RIS TY - JOUR T1 - Thoracoabdominal asynchrony correlates with peripheral vascular resistance changes in a cohort of obese children. AU - Marco Zaffanello , Franco Antoniazzi , Laura Tenero , Michele Piazza , Angelo Pietrobelli , giuseppe Lippi , Emma Gasperi , giorgio Piacentini Y1 - 2018 PY - 2018 N1 - doi: 10.17546/msd.411431 DO - 10.17546/msd.411431 T2 - Medical Science and Discovery JF - Journal JO - JOR SP - 169 EP - 173 VL - 5 IS - 4 SN - 2148-6832-2148-6832 M3 - doi: 10.17546/msd.411431 UR - http://dx.doi.org/10.17546/msd.411431 Y2 - 2018 ER -
EndNote %0 Medical Science and Discovery Thoracoabdominal asynchrony correlates with peripheral vascular resistance changes in a cohort of obese children. %A Marco Zaffanello , Franco Antoniazzi , Laura Tenero , Michele Piazza , Angelo Pietrobelli , giuseppe Lippi , Emma Gasperi , giorgio Piacentini %T Thoracoabdominal asynchrony correlates with peripheral vascular resistance changes in a cohort of obese children. %D 2018 %J Medical Science and Discovery %P 2148-6832-2148-6832 %V 5 %N 4 %R doi: 10.17546/msd.411431 %U 10.17546/msd.411431