Yıl 2018, Cilt 6, Sayı 2, Sayfalar 45 - 52 2018-09-12

Vitamin D Eksikliği Koroner Arter Hastalığı İçin Ön Görüdürücü Müdür?
Can Vitamin D Deficiency Predict Coronary Artery Disease?

Şeref ALPSOY [1] , Aydın AKYÜZ [2] , Demet ÖZKARAMANLI GÜR [3] , Birol TOPÇU [4] , Hasan DEĞİRMENCİ [5]

10 12

Amaç: D vitamininin ve koroner arter hastalığının (KAH) ilişkisiyle ilgili ortaya çıkan verilere dayanarak, KAH'da D vitamini ile C-reaktif protein (CRP) ile temsil edilen inflamasyon ve serum lipid profili arasında  ilişki bulunup bulunmadığını araştırdık.

Materyal ve Metod: Yeni KAH tanısı  konmuş 115 hasta ve 62 sağlıklı birey çalışmaya alındı. Kan lipidleri, CRP ve D vitamini düzeyleri ölçüldü ve hasta ve kontrol gruplarının değerleri karşılaştırıldı.

Bulgular: Hasta grubunda düşük dansiteli lipoprotein kolesterol (DDL-K), CRP ve trigliserit düzeyleri yüksek, vitamin D ve yüksek dansiteli lipoprotein kolesterol (YDL-K) düşüktü.Vitamin D ile YDL-K arasında pozitif korelasyon(r=0.328; p<0.001), vitamin D ile CRP arasında negatif korelasyon (r=-0.484; p<0.001) vardı. Multivariate lojistik regresyon analizinde, sigara (p=0.001, OR = 5.301; 95% CI = 2.215 – 12.687), hipertansiyon varlığı (p=0.040, OR = 2.355; 95% CI=1.039 – 5.336), DDL-K düzeyi (p=0.048, OR =1.021, 95% CI=1.000 – 1.042) ve vitamin D düzeyi (p=0.001, OR = 0.937, 95% CI = 0.902 – 0.973) KAH belirleyicisi olarak bulundular.

 

Sonuç: Azalmış D vitamini seviyeleri, KAH'da düşük YDL-K ve yüksek CRP seviyeleri ile ilişkilidir. Sigara, hipertansiyon, DDL-K ve D vitamini, KAH'ın belirleyicisidirler. 

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Birincil Dil en
Konular Tıp Bilimleri
Dergi Bölümü Araştırma Makalesi
Yazarlar

Yazar: Şeref ALPSOY (Sorumlu Yazar)
Kurum: Namık Kemal Üniversitesi Tıp Fakültesi
Ülke: Turkey


Yazar: Aydın AKYÜZ

Yazar: Demet ÖZKARAMANLI GÜR

Yazar: Birol TOPÇU

Yazar: Hasan DEĞİRMENCİ

Bibtex @araştırma makalesi { nkmj405494, journal = {Namık Kemal Tıp Dergisi}, issn = {}, address = {Namık Kemal Üniversitesi}, year = {2018}, volume = {6}, pages = {45 - 52}, doi = {}, title = {Can Vitamin D Deficiency Predict Coronary Artery Disease?}, key = {cite}, author = {ALPSOY, Şeref and DEĞİRMENCİ, Hasan and GÜR, Demet ÖZKARAMANLI and TOPÇU, Birol and AKYÜZ, Aydın} }
APA ALPSOY, Ş , AKYÜZ, A , GÜR, D , TOPÇU, B , DEĞİRMENCİ, H . (2018). Can Vitamin D Deficiency Predict Coronary Artery Disease?. Namık Kemal Tıp Dergisi, 6 (2), 45-52. Retrieved from http://dergipark.gov.tr/nkmj/issue/39120/405494
MLA ALPSOY, Ş , AKYÜZ, A , GÜR, D , TOPÇU, B , DEĞİRMENCİ, H . "Can Vitamin D Deficiency Predict Coronary Artery Disease?". Namık Kemal Tıp Dergisi 6 (2018): 45-52 <http://dergipark.gov.tr/nkmj/issue/39120/405494>
Chicago ALPSOY, Ş , AKYÜZ, A , GÜR, D , TOPÇU, B , DEĞİRMENCİ, H . "Can Vitamin D Deficiency Predict Coronary Artery Disease?". Namık Kemal Tıp Dergisi 6 (2018): 45-52
RIS TY - JOUR T1 - Can Vitamin D Deficiency Predict Coronary Artery Disease? AU - Şeref ALPSOY , Aydın AKYÜZ , Demet ÖZKARAMANLI GÜR , Birol TOPÇU , Hasan DEĞİRMENCİ Y1 - 2018 PY - 2018 N1 - DO - T2 - Namık Kemal Tıp Dergisi JF - Journal JO - JOR SP - 45 EP - 52 VL - 6 IS - 2 SN - - M3 - UR - Y2 - 2018 ER -
EndNote %0 Namık Kemal Tıp Dergisi Can Vitamin D Deficiency Predict Coronary Artery Disease? %A Şeref ALPSOY , Aydın AKYÜZ , Demet ÖZKARAMANLI GÜR , Birol TOPÇU , Hasan DEĞİRMENCİ %T Can Vitamin D Deficiency Predict Coronary Artery Disease? %D 2018 %J Namık Kemal Tıp Dergisi %P - %V 6 %N 2 %R %U
ISNAD ALPSOY, Şeref , AKYÜZ, Aydın , GÜR, Demet ÖZKARAMANLI , TOPÇU, Birol , DEĞİRMENCİ, Hasan . "Vitamin D Eksikliği Koroner Arter Hastalığı İçin Ön Görüdürücü Müdür?". Namık Kemal Tıp Dergisi 6 / 2 (Eylül 2018): 45-52.