Yıl 2018, Cilt 6, Sayı 3, Sayfalar 109 - 116 2018-12-13

Mean Platelet Volumes Of Infants Wİth Acute Bronchıolıtıs, is There a Correlation Between Them?
Akut Bronşiolit Tanılı İnfantlarda Ortalama Platelet Hacmi, İkisi Arasında Bir Korelasyon Var Mı?

Burçin NALBANTOĞLU [1] , Nuriye Ece MİNTAŞ [2] , Ayşin NALBANTOĞLU [3] , Mustafa Metin DONMA [4] , Nedim SAMANCI [5]

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Acute bronchiolitis is the most common lower respiratory tract infection of children younger than 2 years of age. Although the diagnose is clinical and the severity plays an important role in treatment, there aren't any standardized diagnostic criterias and severity assessment classifications for acute bronchiolitis available in literature. Results of the recent studies suggest that one of the platelet activation indice, MPV, can be used as an acute phase reactant in diseases. MPV has shown to be effected in local inflammations and to our knowledge there's only one recent study in children with acute bronchiolitis that demonstrates a decrease in MPV. Therefore more studies are needed to clarify the relation between MPV and acute bronchiolitis. In this present study we aim to determine the association between MPV and acute bronchiolitis, also identify whether it’s a useful marker on assessing disease severity or not. In this retrospective study we enrolled 555 children diagnosed with Acute bronchiolitis and 516 healthy infants with a matching age and sex. MPV levels were found significantly higher in patient group (8,2 ± 0,8 fL) than the control group (7,9 ± 0,8 fL).  In terms of hospitalization need no significant difference detected between the MPV values of hospitalized group and outpatients, 8,3±0,8 fL; 8,2±0.7 fL respectively. In conclusion, our data show that MPV values significantly elevate in acute bronchiolitis compared to healthy infants. However, MPV can't be used as a guidance in attack severity nor can predict hospitalization, PICU admittion, and systemic steroid need.

Akut bronşiolit, 2 yaş altı çocuklarda en sık görülen alt solunum yolu enfeksiyonudur. Tanı klinik olarak konmasına rağmen, tanı koymak ve tedavi için önemli olan hastalık ciddiyetini değerlendirmek için standart kriterler bulunmamaktadır. Son yıllarda yapılan çalışmalarda ortalama trombosit hacmi (MPV) değerinin akut faz reaktanı olarak kullanılabileceği öne sürülmüştür. Lokal inflamasyon ile ilişkisi gösterilmesine rağmen MPV ve akut bronşiolit ilişkisini gösteren az sayıda çalışma bulunmaktadır. Biz de çalışmamızda MPV ve bronşiolit arasındaki ilişkiyi araştırmak ve MPV'nin hastalık ciddiyetini göstermede faydalı bir parametre olarak kullanılıp kullanılamayacağını değerlendirmek istedik. Bu retrospektif çalışmada 555 akut bronşiolit hastası ve aynı yaş ve cinsiyete sahip 516 sağlıklı hasta çalışmaya dahil edildi. MPV düzeyleri hasta grubunda (8,2 fl), hasta grubuna göre (7,8) anlamlı olarak yüksek saptandı. Ancak hastane yatışı gerektiren ve ayaktan tedavi alan hastalar arasında anlamlı bir fark saptanamadı. Sonuç olarak MPV değeri akut bronşiolit hastalarında artmakta ancak, hastaneye yatış, yoğun bakım ve sterod ihtiyacını öngörememektedir. 

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Birincil Dil en
Konular Tıp
Dergi Bölümü Araştırma Makalesi
Yazarlar

Yazar: Burçin NALBANTOĞLU (Sorumlu Yazar)
Kurum: NAMIK KEMAL ÜNİVERSİTESİ
Ülke: Turkey


Yazar: Nuriye Ece MİNTAŞ
Kurum: NAMIK KEMAL ÜNİVERSİTESİ
Ülke: Turkey


Yazar: Ayşin NALBANTOĞLU
Kurum: NAMIK KEMAL ÜNİVERSİTESİ
Ülke: Turkey


Yazar: Mustafa Metin DONMA
Kurum: NAMIK KEMAL ÜNİVERSİTESİ
Ülke: Turkey


Yazar: Nedim SAMANCI
Kurum: NAMIK KEMAL ÜNİVERSİTESİ
Ülke: Turkey


Bibtex @araştırma makalesi { nkmj453964, journal = {Namık Kemal Tıp Dergisi}, issn = {}, eissn = {2587-0262}, address = {Namık Kemal Üniversitesi}, year = {2018}, volume = {6}, pages = {109 - 116}, doi = {}, title = {Mean Platelet Volumes Of Infants Wİth Acute Bronchıolıtıs, is There a Correlation Between Them?}, key = {cite}, author = {MİNTAŞ, Nuriye Ece and SAMANCI, Nedim and DONMA, Mustafa Metin and NALBANTOĞLU, Burçin and NALBANTOĞLU, Ayşin} }
APA NALBANTOĞLU, B , MİNTAŞ, N , NALBANTOĞLU, A , DONMA, M , SAMANCI, N . (2018). Mean Platelet Volumes Of Infants Wİth Acute Bronchıolıtıs, is There a Correlation Between Them?. Namık Kemal Tıp Dergisi, 6 (3), 109-116. Retrieved from http://dergipark.gov.tr/nkmj/issue/41097/453964
MLA NALBANTOĞLU, B , MİNTAŞ, N , NALBANTOĞLU, A , DONMA, M , SAMANCI, N . "Mean Platelet Volumes Of Infants Wİth Acute Bronchıolıtıs, is There a Correlation Between Them?". Namık Kemal Tıp Dergisi 6 (2018): 109-116 <http://dergipark.gov.tr/nkmj/issue/41097/453964>
Chicago NALBANTOĞLU, B , MİNTAŞ, N , NALBANTOĞLU, A , DONMA, M , SAMANCI, N . "Mean Platelet Volumes Of Infants Wİth Acute Bronchıolıtıs, is There a Correlation Between Them?". Namık Kemal Tıp Dergisi 6 (2018): 109-116
RIS TY - JOUR T1 - Mean Platelet Volumes Of Infants Wİth Acute Bronchıolıtıs, is There a Correlation Between Them? AU - Burçin NALBANTOĞLU , Nuriye Ece MİNTAŞ , Ayşin NALBANTOĞLU , Mustafa Metin DONMA , Nedim SAMANCI Y1 - 2018 PY - 2018 N1 - DO - T2 - Namık Kemal Tıp Dergisi JF - Journal JO - JOR SP - 109 EP - 116 VL - 6 IS - 3 SN - -2587-0262 M3 - UR - Y2 - 2018 ER -
EndNote %0 Namık Kemal Tıp Dergisi Mean Platelet Volumes Of Infants Wİth Acute Bronchıolıtıs, is There a Correlation Between Them? %A Burçin NALBANTOĞLU , Nuriye Ece MİNTAŞ , Ayşin NALBANTOĞLU , Mustafa Metin DONMA , Nedim SAMANCI %T Mean Platelet Volumes Of Infants Wİth Acute Bronchıolıtıs, is There a Correlation Between Them? %D 2018 %J Namık Kemal Tıp Dergisi %P -2587-0262 %V 6 %N 3 %R %U
ISNAD NALBANTOĞLU, Burçin , MİNTAŞ, Nuriye Ece , NALBANTOĞLU, Ayşin , DONMA, Mustafa Metin , SAMANCI, Nedim . "Akut Bronşiolit Tanılı İnfantlarda Ortalama Platelet Hacmi, İkisi Arasında Bir Korelasyon Var Mı?". Namık Kemal Tıp Dergisi 6 / 3 (Aralık 2018): 109-116.