Yıl 2016, Cilt 8, Sayı 1, Sayfalar 76 - 84 2016-01-23

Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy
Elektrokonvulsif Tedavi Anestezisinde Rokuronyum-Sugammadeks

Nilay Taş [1] , Esra Yancar Demir [2]

453 1828

Electroconvulsive therapy (ECT) is a form of treatment which is very effective in many psychiatric disorders. The administration of anesthesia plays a positive role in the success of ECT and improves the oxygenation of the body during the process. Succinylcholine, is a depolarizing neuromuscular blocker of choice, the most common agent used to provide muscular relaxation during ECT. Alternative neuromusculer blokers have been used during anesthesia because of contraindications and serious side effects of succinylcholine. Rocuronium is a nondepolarizing neuromuscular blocker with intermediate time of action which may be used safely during ECT. Although relatively late onset of action and long half life compared to succinylcholine may seem as drawbacks, the new generation reversing agents like suggamadex have made these disadvantages ignorable. Sugammadex, a new generation neuromuscular blocker reversal agent, not having serious side effects as much as the classic reversals, such as cardiovascular side effects, is playing an important role in anesthesiology practice. In recent years, rocuronium - sugammadex combination is being included in the ECT practice extensively. In this paper, the usability of rocuronium-sugammadex combination as an alternative to succinylcholine has been revised.
Elektrokonvulsif tedavi (EKT), pek çok psikiyatrik bozuklukta etkili olan bir tedavi biçimidir. Anestezi uygulaması, hem EKT’nin başarılı olmasında rol oynar hem de işlem sırasında vücudun oksijen kullanımını iyileştirir. Süksinilkolin, EKT sırasında kas gevşekliği sağlamak için en sık kullanılan depolarizan özellikte nöromuskuler blokerdir. Süksinilkolinin ciddi yan etkilere sahip olması ve kontrendike olduğu durumlar sebebiyle, anestezi uygulaması için alternatif nöromuskuler blokerler kullanıma girmiştir. Rokuronyum, orta etki süreli nondepolarizan bir nöromuskuler bloker olup EKT sırasında güvenle kullanılmaktadır. Sugammadeks, bazı nondepolarizan nöromuskuler blokerlerin etkisinin sonlandırılması amacıyla kullanılan yeni nesil bir geri döndürücü ajandır. Geleneksel geri döndürücü ajanların meydana getirdiği kardiyovasküler yan etkiler gibi bir takım yan etkilerinin olmaması sebebiyle anestezi pratiğinde önemli bir yere sahip olmuştur. Rokronyum–sugammadeks  kombinasyonu gün geçtikçe daha fazla oranda EKT sırasında kullanılmaktadır. Bu derlemede, EKT anestezisinde süksinilkoline alternatif olarak rokuronyum–sugammadeks kombinasyonunun kullanılabilirliği gözden geçirilmiştir.
EKT, nöromuskuler blokaj, sugammadeks
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Yazar: Nilay Taş

Yazar: Esra Yancar Demir

Bibtex @ { pgy133530, journal = {Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry}, issn = {1309-0658}, eissn = {1309-0674}, address = {Lut TAMAM}, year = {2016}, volume = {8}, pages = {76 - 84}, doi = {10.18863/pgy.91843}, title = {Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy}, key = {cite}, author = {Taş, Nilay and Yancar Demir, Esra} }
APA Taş, N , Yancar Demir, E . (2016). Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy. Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry, 8 (1), 76-84. DOI: 10.18863/pgy.91843
MLA Taş, N , Yancar Demir, E . "Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy". Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 8 (2016): 76-84 <http://dergipark.gov.tr/pgy/issue/11171/133530>
Chicago Taş, N , Yancar Demir, E . "Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy". Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 8 (2016): 76-84
RIS TY - JOUR T1 - Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy AU - Nilay Taş , Esra Yancar Demir Y1 - 2016 PY - 2016 N1 - doi: 10.18863/pgy.91843 DO - 10.18863/pgy.91843 T2 - Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry JF - Journal JO - JOR SP - 76 EP - 84 VL - 8 IS - 1 SN - 1309-0658-1309-0674 M3 - doi: 10.18863/pgy.91843 UR - http://dx.doi.org/10.18863/pgy.91843 Y2 - 2018 ER -
EndNote %0 Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy %A Nilay Taş , Esra Yancar Demir %T Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy %D 2016 %J Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry %P 1309-0658-1309-0674 %V 8 %N 1 %R doi: 10.18863/pgy.91843 %U 10.18863/pgy.91843
ISNAD Taş, Nilay , Yancar Demir, Esra . "Elektrokonvulsif Tedavi Anestezisinde Rokuronyum-Sugammadeks". Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 8 / 1 (Ocak 2016): 76-84. http://dx.doi.org/10.18863/pgy.91843