Yıl 2014, Cilt 21, Sayı 4, Sayfalar 114 - 117 2015-01-29

RETROPERİTONEAL YUMUŞAK DOKU SARKOMDA KLİNİK DENEYİMLERİMİZ

çağlar özçelik [1] , ismail zihni [2] , oktay karaköse [3] , hüseyin pülat [4] , hasan eroğlu [5]

143 1286

Aim/Objective: Retroperitoneal soft tissue sarcoma; epidemiological, histopathological features of cases in our clinic, treatments and their clinical courses were compared with the literature. Materials and Methods: Records of 7 patients who were operated in Surgical Oncology Clinics of Süleyman Demirel University between 2007-2013 after being detected with primary retroperitoneal- intraperitoneal masses in imagings and being reported as soft tissue tumor in histopathological examination were analyzed retrospectively. Results: The patients were 6 males and 1 female. Abdominal tomography was applied to all patients and in imagings there were both intraperitoneal and retroperitoneal masses in 4 patients (57,1%), left retroperitoneal masses in 2 patients (28,6%) and intraperitoneal mass in 1 patient (14,3%). Distant metastases weren’t detected in any of the patients at the time of diagnosis. While mass excision was done in 2 patients, enbloc organs resection (colon and kidney) was done along with excision in 3 patients, two patients were admitted as unresectable. In pathological examination, 42,9% (in 3 patient) good differential liposarcoma, 28,6% (in 2 patient) leiomyosarcoma and 14.3% (1 patient) dedifferentiated liposarcoma and rhabdomyosarcoma were detected. Recurrence developed in 2 patients who were applied mass excision in 11th month (10th month and 12th month) on the average. Lung metastases developed in one patient in the 6th month who were applied enbloc organ and mass resection. Conclusion: Retroperitoneal soft tissue sarcomas are rarely seen. However, recurrence often develops generally due to incomplete surgery. Therefore, aggressive surgery is recommended in these tumors in order to provide negative surgery border
Amaç: Retroperitoneal yumuşak doku sarkomlarında kliniğimizdeki vakaların epidemiyolojik, histopatolojik özellikleri, uygulanan tedaviler ve klinik seyirleri literatür ile karşılaştırıldı. Gereç ve Yöntem: Süleyman Demirel Üniversitesi Cerrahi Onkoloji Kliniğinde 2008-2013 yılları arasında görüntülemelerde primer retroperitoneal-intraperitoneal kitle saptanıp operasyona alınan ve histopatolojik incelemesi yumuşak doku tümörü olarak raporlanan 7 hastanın kayıtları retrospektif olarak incelendi. Bulgular: Hastaların 6'sı erkek 1 kadındı. Tüm hastalara abdominal tomografi uygulandı ve görüntülemede 4 hastada (%57,1) hem intraperitoneal hem retroperitonel 2 hasta (%28,6) sol retroperitonealde ve 1 hastada (%14,3) intraperitoneal kitle mevcuttu. Tanı anında hiçbir hastada uzak organ metastazı saptanmadı. Hastaların 2'sine kitle eksizyonu, 3'üne kitle ile birlikte en-blok organ rezeksiyonu (kolon ve böbrek) yapılırken 2 hasta rezektable değildi. Patolojik incelemede %42,9 (3 hasta) iyi differansiye liposarkom, %28,6 (2 hasta) leiomyosarkom, %14,3 (1 hasta) rabdomyosarkom ve indiferansiye liposarkom saptandı. Kitle eksizyonu uygulanan 2 hastada ortalama 11.ayında (10.ay ve 12.ay) nüks gelişti. Kitle ile en blok organ rezeksiyonu yapılan bir hastada ise 6.ayında akciğer metastazı gelişti. Sonuç: Retroperitoneal yumuşak doku sarkomları nadir izlenmektedir. Ancak genellikle yetersiz cerrahiye bağlı olarak nüks sıklıkla gelişmektedir. Bundan dolayı negatif cerrahi sınır sağlamak için bu tümörlerde agresif cerrahi önerilmektedir. Anahtar kelimeler: Sarkom, yumuşak doku, retroperiton, rezeksiyon Abstract Aim/Objective: Retroperitoneal soft tissue sarcoma; epidemiological, histopathological features of cases in our clinic, treatments and their clinical courses were compared with the literature. Materials and Methods: Records of 7 patients who were operated in Surgical Oncology Clinics of Süleyman Demirel University between 2007-2013 after being detected with primary retroperitoneal- intraperitoneal masses in imagings and being reported as soft tissue tumor in histopathological examination were analyzed retrospectively. Results: The patients were 6 males and 1 female. Abdominal tomography was applied to all patients and in imagings there were both intraperitoneal and retroperitoneal masses in 4 patients (57,1%), left retroperitoneal masses in 2 patients (28,6%) and intraperitoneal mass in 1 patient (14,3%). Distant metastases weren't detected in any of the patients at the time of diagnosis. While mass excision was done in 2 patients, enbloc organs resection (colon and kidney) was done along with excision in 3 patients, two patients were admitted as unresectable. In pathological examination, 42,9% (in 3 patient) good differential liposarcoma, 28,6% (in 2 patient) leiomyosarcoma and 14.3% (1 patient) dedifferentiated liposarcoma and rhabdomyosarcoma were detected. Recurrence developed in 2 patients who were applied mass excision in 11th month (10th month and 12th month) on the average. Lung metastases developed in one patient in the 6th month who were applied enbloc organ and mass resection. Conclusion: Retroperitoneal soft tissue sarcomas are rarely seen. However, recurrence often develops generally due to incomplete surgery. Therefore, aggressive surgery is recommended in these tumors in order to provide negative surgery border. Keywords: Sarcoma, soft tissue, retroperitoneal, resection
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Dergi Bölümü Araştırma Makaleleri
Yazarlar

Yazar: çağlar özçelik

Yazar: ismail zihni

Yazar: oktay karaköse

Yazar: hüseyin pülat

Yazar: hasan eroğlu

Bibtex
APA özçelik, ç , zihni, i , karaköse, o , pülat, h , eroğlu, h . (). . , 21 (4), 114-117. Retrieved from http://dergipark.gov.tr/sdutfd/issue/21019/226039
MLA özçelik, ç , zihni, i , karaköse, o , pülat, h , eroğlu, h . "". 21 (): 114-117 <http://dergipark.gov.tr/sdutfd/issue/21019/226039>
Chicago özçelik, ç , zihni, i , karaköse, o , pülat, h , eroğlu, h . "". 21 (): 114-117
RIS TY - JOUR T1 - AU - çağlar özçelik , ismail zihni , oktay karaköse , hüseyin pülat , hasan eroğlu Y1 - 2015 PY - 2015 N1 - DO - T2 - SDÜ Tıp Fakültesi Dergisi JF - Journal JO - JOR SP - 114 EP - 117 VL - 21 IS - 4 SN - 1300-7416-2602-2109 M3 - UR - Y2 - 2018 ER -
EndNote %0 SDÜ Tıp Fakültesi Dergisi %A çağlar özçelik , ismail zihni , oktay karaköse , hüseyin pülat , hasan eroğlu %T %D 2015 %J SDÜ Tıp Fakültesi Dergisi %P 1300-7416-2602-2109 %V 21 %N 4 %R %U
ISNAD özçelik, çağlar , zihni, ismail , karaköse, oktay , pülat, hüseyin , eroğlu, hasan . "RETROPERİTONEAL YUMUŞAK DOKU SARKOMDA KLİNİK DENEYİMLERİMİZ". SDÜ Tıp Fakültesi Dergisi 21 / 4 (Ocak 2015): 114-117.