Year 2012, Volume 42, Issue 3, Pages 449 - 456 2012-03-01

Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study
Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study

Nusret AKPOLAT [1] , Yalçın BÜYÜK [2] , İbrahim UZUN [3] , İlhan GEÇİT [4] , Gülay KURNAZ [5]

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To investigate the frequency of latent prostatic carcinoma (PCa) and prostatic intraepithelial neoplasia (PIN) in the Turkish population. Materials and methods: PCa and PIN were evaluated in 116 male autopsy cases in which the cause of death was nontumoral. All patients were Turkish, living in İstanbul, and aged 40-79 years. Results: The prevalence of PCa was 19.8% and the decade rates (decades 5-8) were 9.5%, 12.5%, 18.8%, and 37%, respectively (P < 0.011). The rates of high-grade prostatic intraepithelial neoplasia (HGPIN) were 33.3%, 31.3%, 56.3%, and 25.9% for decades 5-8, respectively (P > 0.05). A total of 68.4% of PCa cases were HGPIN. There was a statistically significant correlation among HGPIN, PCa, and Gleason scores (P < 0.002). Conclusion: The prevalence of latent PCa in the Turkish population is very high (19.7%). In order to determine latent PCa cases, males over 40 years of age must be screened more strictly.
To investigate the frequency of latent prostatic carcinoma (PCa) and prostatic intraepithelial neoplasia (PIN) in the Turkish population. Materials and methods: PCa and PIN were evaluated in 116 male autopsy cases in which the cause of death was nontumoral. All patients were Turkish, living in İstanbul, and aged 40-79 years. Results: The prevalence of PCa was 19.8% and the decade rates (decades 5-8) were 9.5%, 12.5%, 18.8%, and 37%, respectively (P < 0.011). The rates of high-grade prostatic intraepithelial neoplasia (HGPIN) were 33.3%, 31.3%, 56.3%, and 25.9% for decades 5-8, respectively (P > 0.05). A total of 68.4% of PCa cases were HGPIN. There was a statistically significant correlation among HGPIN, PCa, and Gleason scores (P < 0.002). Conclusion: The prevalence of latent PCa in the Turkish population is very high (19.7%). In order to determine latent PCa cases, males over 40 years of age must be screened more strictly.
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Journal Section Articles
Authors

Author: Nusret AKPOLAT

Author: Yalçın BÜYÜK

Author: İbrahim UZUN

Author: İlhan GEÇİT

Author: Gülay KURNAZ

Bibtex @ { tbtkmedical147108, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {TUBITAK}, year = {2012}, volume = {42}, pages = {449 - 456}, doi = {}, title = {Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study}, key = {cite}, author = {AKPOLAT, Nusret and BÜYÜK, Yalçın and UZUN, İbrahim and GEÇİT, İlhan and KURNAZ, Gülay} }
APA AKPOLAT, N , BÜYÜK, Y , UZUN, İ , GEÇİT, İ , KURNAZ, G . (2012). Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study. Turkish Journal of Medical Sciences, 42 (3), 449-456. Retrieved from http://dergipark.gov.tr/tbtkmedical/issue/12298/147108
MLA AKPOLAT, N , BÜYÜK, Y , UZUN, İ , GEÇİT, İ , KURNAZ, G . "Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study". Turkish Journal of Medical Sciences 42 (2012): 449-456 <http://dergipark.gov.tr/tbtkmedical/issue/12298/147108>
Chicago AKPOLAT, N , BÜYÜK, Y , UZUN, İ , GEÇİT, İ , KURNAZ, G . "Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study". Turkish Journal of Medical Sciences 42 (2012): 449-456
RIS TY - JOUR T1 - Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study AU - Nusret AKPOLAT , Yalçın BÜYÜK , İbrahim UZUN , İlhan GEÇİT , Gülay KURNAZ Y1 - 2012 PY - 2012 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 449 EP - 456 VL - 42 IS - 3 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2019 ER -
EndNote %0 Turkish Journal of Medical Sciences Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study %A Nusret AKPOLAT , Yalçın BÜYÜK , İbrahim UZUN , İlhan GEÇİT , Gülay KURNAZ %T Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study %D 2012 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 42 %N 3 %R %U
ISNAD AKPOLAT, Nusret , BÜYÜK, Yalçın , UZUN, İbrahim , GEÇİT, İlhan , KURNAZ, Gülay . "Prevalence of latent prostate cancer and prostatic intraepithelial neoplasia in İstanbul, Turkey: an autopsy study". Turkish Journal of Medical Sciences 42 / 3 (March 2012): 449-456.