Year 2012, Volume 42, Issue 3, Pages 491 - 496 2012-03-01

Effect of ovulation induction on QT dispersion in electrocardiography
Effect of ovulation induction on QT dispersion in electrocardiography

Ayla ÜÇKUYU [1] , Faika Ceylan ÇİFTÇİ [2] , Özgür ÇİFTÇİ [3] , Emel Ebru ÖZÇİMEN [4] , Erzat TOPRAK [5] , Erdem TURHAN [6]

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To investigate whether ovulation induction resulting in supra-physiological concentration range of ovarian hormones has an effect on interlead ventricular depolarization heterogeneity via QT dispersion measurements. Estrogens influence the duration of cardiac repolarization but there is no significant change in the QT interval duration within the range of physiological estradiol variations. Materials and methods: Included in the study were 40 subjects, in whom ovulation induction was planned, and 20 volunteers. During the study, a 12-lead electrocardiogram of each woman was carried out 3 times: for the first time on day 2-3 of the menstrual cycle (menstrual day), for the second time 36 h after hCG administration (ovulatory day), and for the third time at 6-8 days following ovulation (mid-luteal day). The RR and QT wave distances were measured. The QT interval corrected for heart rate (corrected QT) was calculated for each derivation. The difference between the longest and shortest corrected QT intervals was determined as corrected QT dispersion. Results: No difference was seen in the mean QT and corrected QT interval duration and the maximum corrected QT interval duration between menstrual phases. On the ovulatory day at peak estrogen level, the corrected QT dispersion was found to be lower than on mid-luteal and menstrual day. Conclusion: QT dispersion demonstrates the regional repolarization heterogeneity of the myocardium, which reflects the propensity of ventricular arrhythmia decreases on the ovulatory day of the ovulation induction cycle.
To investigate whether ovulation induction resulting in supra-physiological concentration range of ovarian hormones has an effect on interlead ventricular depolarization heterogeneity via QT dispersion measurements. Estrogens influence the duration of cardiac repolarization but there is no significant change in the QT interval duration within the range of physiological estradiol variations. Materials and methods: Included in the study were 40 subjects, in whom ovulation induction was planned, and 20 volunteers. During the study, a 12-lead electrocardiogram of each woman was carried out 3 times: for the first time on day 2-3 of the menstrual cycle (menstrual day), for the second time 36 h after hCG administration (ovulatory day), and for the third time at 6-8 days following ovulation (mid-luteal day). The RR and QT wave distances were measured. The QT interval corrected for heart rate (corrected QT) was calculated for each derivation. The difference between the longest and shortest corrected QT intervals was determined as corrected QT dispersion. Results: No difference was seen in the mean QT and corrected QT interval duration and the maximum corrected QT interval duration between menstrual phases. On the ovulatory day at peak estrogen level, the corrected QT dispersion was found to be lower than on mid-luteal and menstrual day. Conclusion: QT dispersion demonstrates the regional repolarization heterogeneity of the myocardium, which reflects the propensity of ventricular arrhythmia decreases on the ovulatory day of the ovulation induction cycle.
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Primary Language tr
Subjects
Journal Section Articles
Authors

Author: Ayla ÜÇKUYU

Author: Faika Ceylan ÇİFTÇİ

Author: Özgür ÇİFTÇİ

Author: Emel Ebru ÖZÇİMEN

Author: Erzat TOPRAK

Author: Erdem TURHAN

Bibtex @ { tbtkmedical147114, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {TUBITAK}, year = {2012}, volume = {42}, pages = {491 - 496}, doi = {}, title = {Effect of ovulation induction on QT dispersion in electrocardiography}, key = {cite}, author = {ÜÇKUYU, Ayla and ÇİFTÇİ, Faika Ceylan and ÇİFTÇİ, Özgür and ÖZÇİMEN, Emel Ebru and TOPRAK, Erzat and TURHAN, Erdem} }
APA ÜÇKUYU, A , ÇİFTÇİ, F , ÇİFTÇİ, Ö , ÖZÇİMEN, E , TOPRAK, E , TURHAN, E . (2012). Effect of ovulation induction on QT dispersion in electrocardiography. Turkish Journal of Medical Sciences, 42 (3), 491-496. Retrieved from http://dergipark.gov.tr/tbtkmedical/issue/12298/147114
MLA ÜÇKUYU, A , ÇİFTÇİ, F , ÇİFTÇİ, Ö , ÖZÇİMEN, E , TOPRAK, E , TURHAN, E . "Effect of ovulation induction on QT dispersion in electrocardiography". Turkish Journal of Medical Sciences 42 (2012): 491-496 <http://dergipark.gov.tr/tbtkmedical/issue/12298/147114>
Chicago ÜÇKUYU, A , ÇİFTÇİ, F , ÇİFTÇİ, Ö , ÖZÇİMEN, E , TOPRAK, E , TURHAN, E . "Effect of ovulation induction on QT dispersion in electrocardiography". Turkish Journal of Medical Sciences 42 (2012): 491-496
RIS TY - JOUR T1 - Effect of ovulation induction on QT dispersion in electrocardiography AU - Ayla ÜÇKUYU , Faika Ceylan ÇİFTÇİ , Özgür ÇİFTÇİ , Emel Ebru ÖZÇİMEN , Erzat TOPRAK , Erdem TURHAN Y1 - 2012 PY - 2012 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 491 EP - 496 VL - 42 IS - 3 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2019 ER -
EndNote %0 Turkish Journal of Medical Sciences Effect of ovulation induction on QT dispersion in electrocardiography %A Ayla ÜÇKUYU , Faika Ceylan ÇİFTÇİ , Özgür ÇİFTÇİ , Emel Ebru ÖZÇİMEN , Erzat TOPRAK , Erdem TURHAN %T Effect of ovulation induction on QT dispersion in electrocardiography %D 2012 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 42 %N 3 %R %U
ISNAD ÜÇKUYU, Ayla , ÇİFTÇİ, Faika Ceylan , ÇİFTÇİ, Özgür , ÖZÇİMEN, Emel Ebru , TOPRAK, Erzat , TURHAN, Erdem . "Effect of ovulation induction on QT dispersion in electrocardiography". Turkish Journal of Medical Sciences 42 / 3 (March 2012): 491-496.