Yıl 2015, Cilt 45, Sayı 6, Sayfalar 1214 - 1219 2015-12-04

The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection
The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection

LÜTFİYE PİRBUDAK [1] , HÜLYA ÇİÇEK [2] , MUSTAFA IŞIK [3] , YASEMİN ZER [4]

187 401

Background/aim: To compare the effects of tramadol-only treatment and tramadol + gabapentin treatment in patients who had received an epidural steroid injection. Materials and methods: Forty patients with hernia disc-originated acute lumbar discogenic pain were evaluated. All patients received a single dose of steroid and local anesthesia mixture epidurally via the lumbar approach. In both groups, Group T (tramadol, n = 20) and Group TG (tramadol + gabapentin, n = 20), the injection dose was adjusted to 4 mL of triamcinolone acetonide and 0.25% bupivacaine mixture. Orally, 75 mg/day tramadol or 75 mg/day tramadol + 900 mg/day gabapentin were added to the treatment. Leukocyte, erythrocyte sedimentation rate, C-reactive protein, and urine serotonin levels were measured prior to and after treatment. The effectiveness of the treatment was evaluated by visual analog scale (VAS), Oswestry Disability Index (ODI), and straight leg elevation test (SLET). Results: Similar improvements in VAS, ODI, and SLET values were observed in both groups in the second week. The inflammation markers were not different after treatment, neither within the groups nor between the groups. Conclusion: This study revealed that tramadol + gabapentin treatment was not superior to tramadol treatment.
Background/aim: To compare the effects of tramadol-only treatment and tramadol + gabapentin treatment in patients who had received an epidural steroid injection. Materials and methods: Forty patients with hernia disc-originated acute lumbar discogenic pain were evaluated. All patients received a single dose of steroid and local anesthesia mixture epidurally via the lumbar approach. In both groups, Group T (tramadol, n = 20) and Group TG (tramadol + gabapentin, n = 20), the injection dose was adjusted to 4 mL of triamcinolone acetonide and 0.25% bupivacaine mixture. Orally, 75 mg/day tramadol or 75 mg/day tramadol + 900 mg/day gabapentin were added to the treatment. Leukocyte, erythrocyte sedimentation rate, C-reactive protein, and urine serotonin levels were measured prior to and after treatment. The effectiveness of the treatment was evaluated by visual analog scale (VAS), Oswestry Disability Index (ODI), and straight leg elevation test (SLET). Results: Similar improvements in VAS, ODI, and SLET values were observed in both groups in the second week. The inflammation markers were not different after treatment, neither within the groups nor between the groups. Conclusion: This study revealed that tramadol + gabapentin treatment was not superior to tramadol treatment.
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Yazar: LÜTFİYE PİRBUDAK

Yazar: HÜLYA ÇİÇEK

Yazar: MUSTAFA IŞIK

Yazar: YASEMİN ZER

Bibtex @ { tbtkmedical149002, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {TÜBİTAK}, year = {2015}, volume = {45}, pages = {1214 - 1219}, doi = {}, title = {The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection}, key = {cite}, author = {ZER, YASEMİN and IŞIK, MUSTAFA and PİRBUDAK, LÜTFİYE and ÇİÇEK, HÜLYA} }
APA PİRBUDAK, L , ÇİÇEK, H , IŞIK, M , ZER, Y . (2015). The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection. Turkish Journal of Medical Sciences, 45 (6), 1214-1219. Retrieved from http://dergipark.gov.tr/tbtkmedical/issue/12391/149002
MLA PİRBUDAK, L , ÇİÇEK, H , IŞIK, M , ZER, Y . "The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection". Turkish Journal of Medical Sciences 45 (2015): 1214-1219 <http://dergipark.gov.tr/tbtkmedical/issue/12391/149002>
Chicago PİRBUDAK, L , ÇİÇEK, H , IŞIK, M , ZER, Y . "The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection". Turkish Journal of Medical Sciences 45 (2015): 1214-1219
RIS TY - JOUR T1 - The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection AU - LÜTFİYE PİRBUDAK , HÜLYA ÇİÇEK , MUSTAFA IŞIK , YASEMİN ZER Y1 - 2015 PY - 2015 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 1214 EP - 1219 VL - 45 IS - 6 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2018 ER -
EndNote %0 Turkish Journal of Medical Sciences The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection %A LÜTFİYE PİRBUDAK , HÜLYA ÇİÇEK , MUSTAFA IŞIK , YASEMİN ZER %T The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection %D 2015 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 45 %N 6 %R %U
ISNAD PİRBUDAK, LÜTFİYE , ÇİÇEK, HÜLYA , IŞIK, MUSTAFA , ZER, YASEMİN . "The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection". Turkish Journal of Medical Sciences 45 / 6 (Aralık 2015): 1214-1219.