Yıl 2016, Cilt 19, Sayı 4, Sayfalar 151 - 154 2018-05-26

HPV TEST OUTCOMES OF PATIENTS WITH CERVICAL CANCER OR CERVICAL INTRAEPITHELIAL NEOPLASIA
SERVİKS KANSERİ YA DA SERVİKAL İNTRAEPİTHELİAL NEOPLAZİ SAPTANAN HASTALARIN HPV TEST SONUÇLARI

Aykut Tuncer [1] , Ali Ayhan [2]

88 91

Aim: Human Papilloma Virüs (HPV) is the essential factor for cervical cancer. Frequency and distribution of HPV types differ among countries. In the present study, we aim to find the proportion of HPV 16/18 and also other high risk types (hrHPV) in patients with cervical intraepitelial neoplasia (CIN) and cervical cancer. Material and Methods: We reviewed clinical and pathological features of patients who had undergone colposcopic biopsy at Baskent University Hospital in Ankara between 2007-2015. Patients with the diagnosis of CIN and cervical cancer were included in the study if they had HPV test. Patients were grouped according to their HPV result. We expressed the frequencies of HPV groups based on histologic diagnosis of CIN and cervical cancer. Results: 229 patients were included in the present study. CIN 1, CIN 2, CIN 3 and cervical cancer were present in 80 (34.9 % ), 112 (48.9 % ), 30 (13.1 % ), 7 (3.1 % ) of the patients, respectively. Among 149 patients with ≥ CIN 2; HPV 16/18 was present in 77 (51.7 % ), other hrHPV types were present in 37 (24.8 % ) patients. Both HPV 16/18 and other hrHPV types were present in 18 patients (12.1% ). Conclusion: 51 % of the patients with CIN or cervical cancer have at least HPV 16 or HPV 18. This ratio was 45 % for other hrHPV types.

Amaç: Serviks kanserinin oluşumunda gerekli olan temel faktör Human Papilloma Virüs’ün (HPV) sıklığı ve dağılımı ülkelerarası toplumsal farklılıklar gösterebilmektedir. Biz bu çalışmamızda serviks kanseri ve servikal intraepithelial neoplazi (CIN) saptanan hastalarda HPV 16, 18 ve diğer hrHPV (yüksek riskli HPV) tiplerinin sıklığını ortaya koymayı amaçladık. Materyal ve Method: 2007-2015 yıllarında Başkent Üniversitesi Tıp Fakültesi Ankara Hastanesi Jinekolojik Onkoloji Cerrahisi poliklini- ğinde kolposkopik biyopsi yapılan olgular taranmıştır. Servikal intraepitelial neoplazi (CIN) ve serviks kanseri saptanan ve HPV Testi ile değerlendirilen hastalar çalışma kapsamında değerlendirilmiştir. HPV test sonucuna göre hastalar gruplandırılmıştır. CIN ve serviks kanseri saptanan hastalarda tanımlanan HPV gruplarının sayısal dağılımı gösterilmiştir. Bulgular: 229 hasta çalışma kapsamında değerlendirilmiştir. 80 (% 34.9) hastada CIN 1, 112 (% 48.9) hastada CIN 2, 30 (% 13.1) hastada CIN 3, 7 (% 3.1) hastada serviks kanseri saptanmıştır. Kolposkopik biyopsi sonucuna göre ≥ CIN 2 lezyon saptanan 149 hastadan 77’sinde (% 51.7) HPV 16/18 +, 37’ sinde (% 24.8) diğer hrHPV + tespit edilmiş olup 18 hastada (% 12.1) hem HPV 16/18 hem de diğer hrHPV tespit edilmiştir. Sonuç: CIN veya serviks kanseri olan hastaların % 51’ i en azından HPV 16 ya da 18’den birini taşımakta olup bu oran diğer hrHPV tipleri için % 45’ dir.

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Birincil Dil tr
Konular Cerrahi
Dergi Bölümü Araştırma Makalesi
Yazarlar

Yazar: Aykut Tuncer (Sorumlu Yazar)

Yazar: Ali Ayhan

Bibtex @araştırma makalesi { trsgo426145, journal = {Türk Jinekolojik Onkoloji Dergisi}, issn = {2148-5372}, address = {Türk Jinekolojik Onkoloji Derneği}, year = {2018}, volume = {19}, pages = {151 - 154}, doi = {}, title = {SERVİKS KANSERİ YA DA SERVİKAL İNTRAEPİTHELİAL NEOPLAZİ SAPTANAN HASTALARIN HPV TEST SONUÇLARI}, key = {cite}, author = {Tuncer, Aykut and Ayhan, Ali} }
APA Tuncer, A , Ayhan, A . (2018). SERVİKS KANSERİ YA DA SERVİKAL İNTRAEPİTHELİAL NEOPLAZİ SAPTANAN HASTALARIN HPV TEST SONUÇLARI. Türk Jinekolojik Onkoloji Dergisi, 19 (4), 151-154. Retrieved from http://dergipark.gov.tr/trsgo/issue/37065/426145
MLA Tuncer, A , Ayhan, A . "SERVİKS KANSERİ YA DA SERVİKAL İNTRAEPİTHELİAL NEOPLAZİ SAPTANAN HASTALARIN HPV TEST SONUÇLARI". Türk Jinekolojik Onkoloji Dergisi 19 (2018): 151-154 <http://dergipark.gov.tr/trsgo/issue/37065/426145>
Chicago Tuncer, A , Ayhan, A . "SERVİKS KANSERİ YA DA SERVİKAL İNTRAEPİTHELİAL NEOPLAZİ SAPTANAN HASTALARIN HPV TEST SONUÇLARI". Türk Jinekolojik Onkoloji Dergisi 19 (2018): 151-154
RIS TY - JOUR T1 - SERVİKS KANSERİ YA DA SERVİKAL İNTRAEPİTHELİAL NEOPLAZİ SAPTANAN HASTALARIN HPV TEST SONUÇLARI AU - Aykut Tuncer , Ali Ayhan Y1 - 2018 PY - 2018 N1 - DO - T2 - Türk Jinekolojik Onkoloji Dergisi JF - Journal JO - JOR SP - 151 EP - 154 VL - 19 IS - 4 SN - 2148-5372- M3 - UR - Y2 - 2018 ER -
EndNote %0 Türk Jinekolojik Onkoloji Dergisi SERVİKS KANSERİ YA DA SERVİKAL İNTRAEPİTHELİAL NEOPLAZİ SAPTANAN HASTALARIN HPV TEST SONUÇLARI %A Aykut Tuncer , Ali Ayhan %T SERVİKS KANSERİ YA DA SERVİKAL İNTRAEPİTHELİAL NEOPLAZİ SAPTANAN HASTALARIN HPV TEST SONUÇLARI %D 2018 %J Türk Jinekolojik Onkoloji Dergisi %P 2148-5372- %V 19 %N 4 %R %U
ISNAD Tuncer, Aykut , Ayhan, Ali . "SERVİKS KANSERİ YA DA SERVİKAL İNTRAEPİTHELİAL NEOPLAZİ SAPTANAN HASTALARIN HPV TEST SONUÇLARI". Türk Jinekolojik Onkoloji Dergisi 19 / 4 (Mayıs 2018): 151-154.