Nephrotoxic Effects of Pesticides

Tülin Gönültaş [1] , Necdet Aytaç [2] , Muhsin Akbaba [3]

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Pesticides are used extensively throughout the world and, in recent years, their use has increased considerably. Pesticides are responsible for several adverse effects on human health, and they represent a potential risk to human. Liver and kidney are firstly most harmed tissues by pesticides, because pesticides are removed from the body by being metabolized in the liver and kidney main road. A broad range of pesticides, including organophosphates, organochlorines, carbamates, pyrethroids and triazine herbicides have been shown to cause renal damage and dysfunction in animal toxicity studies.The most commonly reported pesticides implicated in human renal damage are organophosphates, though other pesticides are known to be nephrotoxic at high levels. Pesticide poisoning case studies, animal models, and in vitro laboratory research provide evidence for a damaging effect of both acute and chronic pesticide exposure on renal function Yet, the impact of long-term pesticide exposure on the human kidney remains unknown. Evidence suggests that pesticide exposure may harm the kidneys through oxidative stress and resulting cell damage. Acute tubular necrosis has also been seen in animal studies of pesticide nephrotoxicity, along with other evidence of renal damage from pesticide exposure. Commonly observed renal symptoms in pesticide poisoning include acute tubular necrosis, hematuria, and proteinuria. Clinically, acute kidney injury is a frequent outcome of pesticide poisoning among humans, and is associated with subsequent renal disease. Chronic effects of pesticides on kidney: Albuminurrhea, increased urea creatinine levels, decreased secretory function Because of potential health risks, pesticides should be used consciously and under supervision.

 

 

Keywords: Nephrotoxic, Pesticides, Poisoning

 

Nephrotoxic Effects of Pesticides
  • Tülin Gönültaş, Necdet Aytaç, Muhsin Akbaba
  • Cukurova University Faculty of Medicine, Public Health Department, Adana
Konular
Dergi Bölümü Articles
Yazarlar

Yazar: Tülin Gönültaş
E-posta: NO@xn--mail-swc.com

Yazar: Necdet Aytaç
E-posta: NO@xn--mail-swc.com

Yazar: Muhsin Akbaba
E-posta: NO@xn--mail-swc.com

Bibtex @ { turjoem318622, journal = {The Turkish Journal Of Occupational / Environmental Medicine and Safety}, issn = {2149-4711}, address = {Engin TUTKUN}, year = {}, volume = {Volume 2}, pages = {3 - 3}, doi = {}, title = {Nephrotoxic Effects of Pesticides}, key = {cite}, author = {Gönültaş, Tülin and Aytaç, Necdet and Akbaba, Muhsin} }
APA Gönültaş, T , Aytaç, N , Akbaba, M . (). Nephrotoxic Effects of Pesticides. The Turkish Journal Of Occupational / Environmental Medicine and Safety, Volume 2 (Issue 1(2)), 3-3. Retrieved from http://dergipark.gov.tr/turjoem/issue/31068/318622
MLA Gönültaş, T , Aytaç, N , Akbaba, M . "Nephrotoxic Effects of Pesticides". The Turkish Journal Of Occupational / Environmental Medicine and Safety Volume 2 (): 3-3 <http://dergipark.gov.tr/turjoem/issue/31068/318622>
Chicago Gönültaş, T , Aytaç, N , Akbaba, M . "Nephrotoxic Effects of Pesticides". The Turkish Journal Of Occupational / Environmental Medicine and Safety Volume 2 (): 3-3
RIS TY - JOUR T1 - Nephrotoxic Effects of Pesticides AU - Tülin Gönültaş , Necdet Aytaç , Muhsin Akbaba Y1 - 2018 PY - 2018 N1 - DO - T2 - The Turkish Journal Of Occupational / Environmental Medicine and Safety JF - Journal JO - JOR SP - 3 EP - 3 VL - Volume 2 IS - Issue 1(2) SN - 2149-4711-2149-4711 M3 - UR - Y2 - 2018 ER -
EndNote %0 The Turkish Journal Of Occupational / Environmental Medicine and Safety Nephrotoxic Effects of Pesticides %A Tülin Gönültaş , Necdet Aytaç , Muhsin Akbaba %T Nephrotoxic Effects of Pesticides %D 2018 %J The Turkish Journal Of Occupational / Environmental Medicine and Safety %P 2149-4711-2149-4711 %V Volume 2 %N Issue 1(2) %R %U